doi:10.1053/S0272-6386(13)90028-7FogoDepartment of Pathology, Vanderbilt University Medical Center, Nashville, TN;AgnesDepartment of Pathology, Vanderbilt University Medical Center, Nashville, TN;elsevierAmerican Journal of Kidney Diseases
Single-cell RNA sequencing (scRNA-seq) and single-nucleus RNA sequencing (snRNA-seq) provide valuable insights into the cellular states of kidney cells. However, the annotation of cell types often requires extensive domain expertise and time-consuming manual curation, limiting scalability and generaliza...
If antibodies are present, the chances of rejection are greatly increased. Platelets ABO blood group + tissue type compatibility Bone marrow ABO blood group + tissue type compatibility + cross-matching Kidney ABO blood group + tissue type compatibility + cross-matching Liver ABO blood group + size...
The severity of acute cellular rejection defined by Banff classification is associated with kidney allograft outcomes. survival.Borderline changes, TCMR I (interstitial rejection), and TCMR II/III (vascular rejection) were defined as low, moderate, and high ACR severity... Kaiyin,Wu,Klemens,......
Medical Importance of Other Casts Epithelial casts:indicate severe damage and death of the tubule cells called tubular necrosis; viral disease such as cytomegalovirus (CMV) nephritis; kidney transplant rejection. Red blood cell casts:indicate damage of glomerulus known as proliferative glomerulonephritis; ...
(Th2 response), but they also contribute to graft rejection (Th1 response) [55]. However, DAMPs generally activate the innate immune response, and consequently, naïve T cells, based on current knowledge, only a few DAMPs appear to be dominant in determining the T helper cell polarization....
Inflammation of yourkidneys(nephritis) maycause high blood pressureor kidney failure. You might not havepainwith an inflammatory disease because some organs don’t have many pain-sensing nerves. How Is Inflammation Diagnosed? If you seem to have chronic inflammation, your doctor will ask about your...
Transcriptional heterogeneity among malignant cells of a tumor has been studied in individual cancer types and shown to be organized into cancer cell states; however, it remains unclear to what extent these states span tumor types, constituting general features of cancer. Here, we perform a pan-ca...
it is possible that ORs tuned to such compounds are highly expressed in both sexes. Hence, we expressed ItypOR36 in Human Embryonic Kidney (HEK) 293 cells for functional characterization and hypothesized that this receptor would be tuned to a compound of importance to the ecology of the beetle...
it is possible that ORs tuned to such compounds are highly expressed in both sexes. Hence, we expressed ItypOR36 in Human Embryonic Kidney (HEK) 293 cells for functional characterization and hypothesized that this receptor would be tuned to a compound of importance to the ecology of the beetle...