Analysis of single-nucleus RNA-seq of glaucoma-relevant eye tissues reveals that the POAG and IOP colocalizing genes and genome-wide associations are enriched in specific cell types in the aqueous outflow pathways, retina, optic nerve head, peripapillary sclera, and choroid. This study nominates ...
Symmetry is a concept that is often thought of in terms of mathematics, but it is also part of biology. The bodies of most multicellular living organisms exhibit symmetry.Answer and Explanation: There are three types of symmetry in biology: bilateral, spherical, and radial. Living organisms that...
both common features of tumor cells1. Despite the fact that these alterations are known to participate in early steps of tumorigenesis and in cancer heterogeneity, the mechanisms underlying mitotic errors that lead to structural chromosome alterations still remain elusive. It is interesting to...
SSRs) markers, their abundance and wide coverage of the genome, their multi-allelic nature, and the high reproducibility of the results make SSRs an irreplaceable tool for quantifying genetic diversity in the population, discovering the patterns of differentiation, and mapping the loci of interest [...
Assuming HWE and linkage equilibrium (LE), five thousand pedigrees (Supplementary Figure S2) were simulated using an in-house R script. For autosomal markers, the alleles of founders were randomly assigned according to the allele frequencies of each locus. Founders transmitted a single allele to hi...