of America, 2 Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, California, United States of America Abstract The lack of reliable, high-throughput tools for characterizing anti-dengue virus (DENV) antibodies in large numbers of serum ...
Germany 6 Department of Infectious Diseases, West German Centre of Infectious Diseases, University Hospital Essen, University of Duisburg-Essen, D-45147 Essen, Germany; adalbert.krawczyk@uni-due.de 7 Institute for Virology, University Hospital of Essen, University of Duisburg-Essen, D-45147 Essen, ...
One reason is that the target disease has changed from an infectious one to a chronic one. Research has also become more difficult because diseases have become complicated in their mechanism of action. As a result, the cost of R&D investment has increased, while the success rate has decreased...