hepatocellular carcinoma (HCC)long non-coding RNA (lncRNA)circular RNA (circRNA)microRNA (miRNAs)competing endogenous (ceRNA) networkTranscriptome profiling of hepatocellular carcinoma (HCC) by next generation sequencing technology (NGS) has been broadly performed by previous researches, whic...
HCC2D codes use an additional field called Color Palette Pattern. How many types of QR Codes are there? 30+ different types of QR Codes Out of the various types of QR Codes available, it can be quite hard to choose the right QR code for your use case. You can explore the different ...
Herein, we demonstrate KIF4A (Chromosome-associated kinesin KIF4A) as a potential biomarker, is up-regulated in most samples of HCC. The expression level of KIF4A in tumor tissue is significantly associated with the survival time, and a significant correlation between KIF4A expression and ...
Results: We demonstrated that down-regulation of HELIS strongly correlates with carcinogenesis; whereas in tumors with non-hepatocyte origin (HBL, CCA) or in a number of poorly differentiated HCC, this lncRNA is not expressed. We showed that recently discovered LINC01093 is dramatically down-...
V940 (mRNA-4157) is a novel investigational messenger RNA (mRNA)-based individualized neoantigen therapy (INT) consisting of a synthetic mRNA coding for up to 34 neoantigens that is designed and produced based...
MicroRNAs (miRNAs) are a highly abundant class of small (~22 nt), endogenous and evolutionarily con- served single-stranded non-coding RNAs that regulate the gene expression normally at post-transcriptional level by base pairing with their target mRNAs at 3′ untranslated regions (UTRs), ...
Both pPRSs were associated with an increased risk of MASLD with the largest association being with hepatocellular carcinoma (HCC); however, the association was stronger for the discordant pPRS (Fig. 3a, Supplementary Fig. 2 and Supplementary Tables 17 and 18). Of note, only the discordant pPR...
be tested in gene knockdown experiments in the context of any cancer phenotype (the “Methods” section). We used 7 cell lines representing 3 types of cancer, namely H460 and HCC1299 from the lung; MDAMB231, MDAMB468, BT549, and HCC187 from the breast; and DU145 from prostate cancer...
The tumors are mostly poorly or un- differentiated, fall short of glandular differentiation, and grow as diffuse sheets [5,27]. SRCC cancer tissues are derived from lung epithelial cells [2,26]. HC Diffuse hepatocellular carcinoma (DHCC) also known as cirrhotomimetic HCC or cirrhosis-like ...
Both pPRSs were associated with an increased risk of MASLD with the largest association being with hepatocellular carcinoma (HCC); however, the association was stronger for the discordant pPRS (Fig.3a, Supplementary Fig.2and Supplementary Tables17and18). Of note, only the discordant pPRS was as...