The present invention relates to a method for identifying the type of glioblastoma multiforme in mammals, preferably human subjects. More particularly, it relates to a kit for characterizing progressive glioma in mammals, preferably human subjects. More particularly, it relates to a kit for ...
Currently, the main target of anti-angiogenic therapy is the vascular endothelial growth factor (VEGF) pathway. Some patients do benefit from anti-VEGF/VEGFR therapy; however, a large number of patients do not have response or acquire drug resistance after treatment. Moreover, anti-VEGF/VEGFR ...
The present study aimed to identify the association between the acetylation level and HCMV IE86 expression in various histological types of glioma. Tissue samples were obtained from 60 patients with glioma, consisting of 25 patients with glioblastoma multiforme (GBM), 16 patients with anaplastic ...
et al. An integrated genomic analysis of human glioblastoma multiforme. Science 321, 1807–1812 (2008). Article CAS PubMed PubMed Central Google Scholar Kane, D.P. & Shcherbakova, P.V. A common cancer-associated DNA polymerase ɛ mutation causes an exceptionally strong mutator phenotype, ...
A previous study has also implicated MXD3 alternative splicing in glioblastoma multiforme (GBM) [32]. In addition, MXD3′s overexpression was shown to promote proliferation in mouse cerebellar granule neuron precursors (GNPs) [29], and to negatively regulate differentiation in mouse spleen-derived ...
I have very recently been diagnosed with glioblastoma multiforme (diffuse, multifocal) grade IV who. Primary treatment plan starts next week (mid August 2017) consisting of combined chemo/radio and onward chemo weeks for 6 four-week periods. Scared as hell as you might imagine. Not looking to...
Ongoing studies are investigating ADI-PEG20 in patients with cancers such as sarcoma or glioblastoma multiforme, which are dependent on arginine. Following the positive data from the Phase III trial, this innovative chemotherapy could benefit other types of cancer, the researchers concluded. ...
The Cancer Genome Atlas (TCGA) has used the latest sequencing and analysis methods to identify somatic variants across thousands of tumours. Here we present data and analytical results for point mutations and small insertions/deletions from 3,281 tumours
and genes. Propagation-based studies in cancer rapidly cascaded to connect gene sequence variations to gene expression changes using multiple diffusions [17]; to generate features used to train machine learning models that predict gene-disease associations in breast cancer, glioblastoma multiforme, and ...
A method for in silico exploration of potential glioblastoma multiforme attractors using single-cell RNA sequencing Marcos Guilherme Vieira Junior Adriano Maurício de Almeida Côrtes Fabrício Alves Barbosa da Silva Scientific Reports(2024) Significance analysis for clustering with single-cell RNA-sequencing...