Cell therapy has emerged as a viable approach for treating damaged organs or tissues, particularly with advancements in stem cell research and regenerative medicine. The innovative technique of cell sheet engineering offers the potential to create a cell
There is not yet consensus within the gene editing community over what the ethical and legal limits to techniques like CRISPR should be. The statement contributes a reasonably clear position: research into using gene editing to cure diseases should continue. But by saying we should hold off on n...
20 May 2016 Glycosyltransferase Gene Expression Profiles Classify Cancer Types and Propose Prognostic Subtypes Jahanshah Ashkani1,2 & Kevin J. Naidoo1,2 Aberrant glycosylation in tumours stem from altered glycosyltransferase (GT) gene expression but can the expression profiles of these signature ...
The generation of mosaic or chimeric vectors through the transcapsidation or marker-rescue/domain-swapping approach, respectively, is notable in this regard. More recently, combinatorial strategies for engineering AAV vectors using error-prone PCR, DNA shuffling, and other molecular cloning techniques ...
a. Production of vaccines c. Gene Therapy 1. Primary cell culture Primary cell culture is the first culture obtained directly from animal tissue via mechanical and chemical disintegration or enzymatic methods. The cells of the primary cell culture are slow-growing cells that carry all the character...
Radiological Techniques Department, Al-Mustaqbal University College, 51001, Hillah Babylon, Iraq Mustafa K. A. Mohammed Microelectronics & VLSI Lab, National Institute of Technology, Patna, 800005, India Reeya Agrawal & Sangeeta Singh Contributions Reeya AGRAWAL: conceptualization, methodology, data curat...
This chapter takes the readers through a comprehensive journey through the multifaceted landscape of cancer with insights into the fundamental differences distinguishing normal cells from their malignant counterparts, exploring the intricate web of common and rare cancer types. The discussion then extends to...
Cell culture is one of the most common and most complex techniques used in life sciences, andculture medium is a key factor for maintaining the health and proliferation of mesenchymal stem cells (MSCs).When completely broken down, all MSCs culture media essentially contain the same basic component...
Based on previously published single-cell RNA sequencing (scRNA-seq) results, we categorized epithelial cells of the mouse small intestine into ten distinct cell types utilizing unsupervised graph-based clustering techniques (Fig. 1A) (Liu et al. 2023). By analyzing their transcriptome profiles of ...
Experimental treatments, like gene silencing techniques, aim to reduce the production of the abnormal huntingtin protein. Also, stem cell therapies and neuroprotective strategies are also being explored to slow disease progression and promote brain cell survival. ...