A significant amount of effort is put into the design of experiments, whether they are being conducted at a private research facility, a university lab, or a high school classroom. This effort is undertaken to avoid as many mistakes and errors as possible. Unfortunately, regardless of how well...
Identifying pathogenic variants from the vast majority of nucleotide variation remains a challenge. We present a method named Multimodal Annotation Generated Pathogenic Impact Evaluator (MAGPIE) that predicts the pathogenicity of multi-type variants. MAG
Many perform experiments in model organisms, such asCaenorhabditis elegans,Drosophila, rodents, zebrafish, or humans, and inspect data to understand the inheritance of biological traits. An environmental geneticist specializes in assessing the interactions between genes and environmental factors that cause se...
Models in this strand frequently offer unique equilibrium predictions, providing clear-cut benchmarks for bargaining experiments.11 The experimental literature on two-sided reputation formation in bargaining is slim. To the best of our knowledge, the only existing experiment is found in Embrey et al...
Single-cell RNA sequencing data can unveil the molecular diversity of cell types. Cell type atlases of the mouse spinal cord have been published in recent years but have not been integrated together. Here, we generate an atlas of spinal cell types based on single-cell transcriptomic data, unify...
To pilot our method, we calculated LOD scores between donor-matched and donor-mismatched pairs of public datasets from the ENCODE12 database, which hosts data from thousands of diverse NGS experiments (Methods). Classification performance was measured in terms of the false flag rate (FFR), the ...
(https://petrowiki.org/Oil), (Standing, 1971), (Vogel, 1968), etc. As current predictive capabilities are limited in terms of accuracy, typically viscosity values that are needed in petroleum engineering applications heavily rely on Lab measurements. One of the elements of the measurement of ...
from each other, (2) contain similar number of sequences, and (3) match the full dataset's target distribution. C: Eight types of protein representations are computed. D: Cross-validation using a random forest regressor is applied to obtain mean values and standard errors on the test ...
In Fig. 1b of this Article, 'Csf1r' was misspelt 'Csfr1', and in Extended Data Fig. 11b, the genes in the first column had shifted down three rows. These errors have been corrected online. References Iadecola, C. The pathobiology of vascular dementia. Neuron 80, 844–866 (2013) CA...
Centromeres are the chromosomal domains required to ensure faithful transmission of the genome during cell division. They have a central role in preventing aneuploidy, by orchestrating the assembly of several components required for chromosome separation