Two types of neurons were differentiated, on the basis of electrophysiological properties, in the substantia nigra pars compacta of the guinea pig maintained in slices. While the majority of neurons, presumably dopaminergic neurons, produced a broad spike accompanied by a relatively long-lasting after...
Increased activity of dopaminergic neurons contributes to the pathophysiology of psychotic disorders and schizophrenia. Drug and alcohol abuse can temporarily increase dopamine levels in the blood, leading to confusion and the inability to focus. However, an appropriate secretion of dopamine in the ...
Which neurons are involved in parkinsonism? a) Cholinergic neurons b) GABAergic neurons c) Dopaminergic neurons d) All of the above How many neurons are there in the human brain? What is the most interesting neuron in the brain? What are the parts of the neuron?
responsible for protecting vulnerable, non-renewable neurons from many insults, be it removal of toxic waste products or restricting the entry of pathogens and xenobiotics. This last specialization, more commonly referred to as the blood-brain barrier (BBB), is unique in that it restricts both par...
Neurological diseases were associated with different cell types, which is consistent with other lines of evidence. Notably, Parkinson’s disease was genetically associated not only with cholinergic and monoaminergic neurons (which include dopaminergic neurons) but also with enteric neurons and ...
They recapitulate in vitro the organization and function of a respective organ or part of an organ. Human midbrain organoids (hMOs) have been described to contain midbrain-specific dopaminergic neurons that release the neurotransmitter dopamine. However, the human midbrain contains also additional ...
Efficient and stable transduction of dopaminergic neurons in rat substantia nigra by rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9 (DNs) in the adult Wistar rat substantia nigra (SN) of seven rAAV vector serotypes (rAAV 2/1, 2/2, 2/5, 2/6.2, 2/7, 2/8 and 2/9)....
Which type of receptors can be activated by angiotensinamide? a. Adrenergic receptors b. Cholinergic receptors c. Dopaminergic receptors d. Angiotensin receptors Which of the following sensory functions involves neurons in the posterior root ganglion? A. Smell B. Hearing C. Touch D. Taste E. Visi...
We investigate the population coding properties and temporal stability of neurons recorded from male macaques in two mapping tasks during and after stimulus-response associative learning, and then we use a Strategy task with the same stimuli and responses as control. We identify a heterogeneous ...
These results demonstrate that in nigral dopaminergic neurons, nicotine can elicit Ca 2+ mobilization via activation of two distinct nAChR subtypes: that of β2-subunit-containing nAChR followed by activation of Na + channel and T-type Ca 2+ channels, and/or activation of α7-subunit-...