Fig. 2: Cellular pathophysiology is non-invasively resolvable in cfRNA. For a given box plot, any cell type signature score is the sum of log-transformed CPM-TMM normalized counts. The horizontal line denotes the median; the lower hinge indicates the 25th percentile; the upper hinge indicates...
Cellular Adaptation: Increases in Number or Size Hydropic Degeneration Causes & Significance | What Causes a Cell to Swell? Cells vs. Virus | Definition, Differences & Characteristics Animal Cells: Lesson for Kids Animal & Human Cells Activities & Games Cells Lesson Plan for Elementary School Ce...
Single-cell RNA-sequencing (scRNA-seq) is a powerful technique that provides high-resolution expression profiling of individual cells. It significantly advances our understanding of cellular diversity and function. Despite its potential, the analysis of scRNA-seq data poses considerable challenges related ...
Photosynthetic and cellular photoadaptive characteristics of three ecotypes of the marine diatom, Skeletonema costatum (Grev.) CleveecotypesphotoadaptationphotosynthesisrespirationSkeletonema costatumPhysiological variation among genetically distinct clones of Skeletonema costatum (Grev.) Cleve, representative of...
Understanding the molecular and cellular processes involved in lung epithelial regeneration may fuel the development of therapeutic approaches for lung diseases. We combine mouse models allowing diphtheria toxin-mediated damage of specific epithelial cell types and parallel GFP-labeling of functionally dividing...
SLC12A2, a membrane cotransporter facilitating the transport and reabsorption of sodium and chloride across cellular membranes, participates in maintaining the proper ionic balance and cell volume (Payne et al. 1995; Yang et al. 2020). Analysis of scRNA-seq results indicated the increased expression...
an adaptation that researchers propose could have evolved through the hornets' long-standing relationship with yeasts. Out in nature, yeasts break down the sugars that exist in fruits and nectars, producing alcohol in the process, and the hornets have a very unique way of interacting with yeasts...
reanalyze two previously published datasets, profiled by osmFISH6and MERFISH5, to demonstrate SSAM’s strength in comparison to earlier methods. For a newly generated multiplexed smFISH dataset we demonstrate that SSAM can unravel novel biological insights into the spatial cellular organization of the...
Cell mixing induces correlation between genes that are expressed by the same cell type but that are not otherwise co-expressed at the cellular level. In the residuals of reverse deconvolution, this unwanted correlation abates, revealing correlation induced by coordinated expression within cell types (...
Cellular adaptation to changes in osmotic pressure to maintain function is known as osmoregulation. Ways in which cells may adapt to osmotic pressure include the use of ion channels and other pumps in the membrane to regulate concentrations of ions inside the cell; the development of a more ...