osteoporosis is a common disease of bone possessing a strong genetic component. Cytochrome P450 aromatase, which is encoded by the CYP19Al gene, converts androgens to estradiol. Considerable evidence suggests that extragonadal estrogens play an important role in determining bone mineral density (BMD)...
What is bone marrow disease? What type of stem cells are found in bone marrow? What are bone marrow stem cells? What is normocellular bone marrow? What is another name for bone marrow? What do stem cells do in bone marrow? What type of cells are produced by red bone marrow?
Aplastic anemia is a life-threatening form of complete bone marrow failure. As a result, the blood contains inadequate numbers of red blood cells (anemia) as well as insufficient white blood cells (leukopenia) and platelets (thrombocytopenia). Complete bone marrow failure causes all three cell lin...
IgE is the rarest type of multiple myeloma. It causes the same signs and symptoms as other types of multiple myeloma. It tends to be aggressive and progresses to plasma cellleukemiaor spreads outside the bone marrow quickly.
The human immune system consists of lymphoid organs, tissues, cells and protein molecules like antibodies. Lymphoid organs: These are the organs where the origin and/or maturation and proliferation of lymphocytes occur.Primary lymphoid organs include bone marrow and thymus, where B-lymphocyte and T-...
Endotypes are characterized by the immunological, inflammatory, metabolic, and remodelling pathways that explain the mechanisms underlying the clinical presentation (phenotype) of a disease. Recessive dystrophic epidermolysis bullosa (RDEB) is a severe b
Leukemia is caused by genetic and metabolic alterations in lymphocyte or myeloid progenitors in the bone marrow. Environmental and lifestyle risks factors of leukemia include smoking, indoor and outdoor air pollution, exposure to radiation and certain chemicals, radiation therapy, chemotherapy and some ...
Then, they’ll use a thin needle to take a small sample of bone marrow from inside your hip bone. Looking at the sample in the lab can show how many cells are immature and the details of how the cells are changing. This gives you information about how severe your cancer is and which...
CRISPR gene editing for sickle cell disease In December 2023, the FDA approved two gene therapy treatments for sickle cell disease. The two therapies, Casgevy and Lyfgenia, both work by modifying stem cells taken from bone marrow, the spongy inside of bones. These stem cells are then modified...
Osteoblasts, osteocytes, and osteoclasts are three types of bone cells. Which of the three are responsible for Osteoporosis and why?Osteoporosis:Osteoporosis is a bone disease. Osteoporosis is characterized by weak bones that break easily. Osteop...