Patients with higher myCAF compositions tend to have worse response to six antineoplastic drugs predicted by a lncRNA-based Elastic Net prediction model (LENP). In addition, integrative mutational analysis identified 14 and 413 genes associated with the differentiation degree of myCAF and inflammatory...
Expression of TFRC helps to improve the antineoplastic effect of Ara-C on AML cells through a targeted delivery carrier Xinzhou Wu Zhouguang Jiao Yuhua Li Journal of Nanobiotechnology(2023) Development and application of nanomaterials, nanotechnology and nanomedicine for treating hematological malignancies...
Evaluation of mitoxantrone for the treatment of multiple sclerosis. Mitoxantrone (Novantrone((R))), an antineoplastic agent, has been approved for treating patients with secondary progressive multiple sclerosis (MS). Mitoxa... Jain,K Kewal - 《Expert Opinion on Investigational Drugs》 被引量: ...
This project was financed with funds from Ministero dell'Università e della Ricerca Scientifica e Tecnologica to MP (in particular, FIRB 2007: Dalla Proteomica alla Biologia Cellulare; FAR 2007: Generation of a technological platform to study the effects of antineoplastic drugs and to investigate ...
and other drugs with tetrahydroisoquinoline (THIQ) motifs.26–29 The endotype for IgE-mediated reactions is mast cell and basophil mediator release that causes flushing, pruritus, hives, angioedema, shortness of breath, wheezing, nausea, vomiting, diarrhea, hypotension, oxygen desaturation, and cardi...
2020) for gene-drug interactions (inhibitor, activator, etc.) and druggable gene categories (clinically actionable, drug resistance, etc.) with default settings. The DGIdb integrates resources from 20 databases and consists of existing drugs including those that are FDA-approved, antineoplastic, and/...
This project was financed with funds from Ministero dell'Università e della Ricerca Scientifica e Tecnologica to MP (in particular, FIRB 2007: Dalla Proteomica alla Biologia Cellulare; FAR 2007: Generation of a technological platform to study the effects of antineoplastic drugs and to investigate ...
To test the possibility that the tubulin isotype composition is an important determinant in antineoplastic efficacy, we determined thermodynamic parameters for vinca alkaloid interactions with purified β-tubulin isotypes, αβII or αβII, as well as mixtures of αβII and αβIII, αβII and ...
Antineoplastic AgentsPain MeasurementNeoplasmsNeuropathic pain--pain resulting from a lesion, damage, or dysfunction of the somatosensory nervous system--can arise through several distinct etiologies ranging from toxicity, surgery, radiation, and trauma to congenital disorders. Neuropathic pain is widely ...
To test the possibility that the tubulin isotype composition is an important determinant in antineoplastic efficacy, we determined thermodynamic parameters for vinca alkaloid interactions with purified -tubulin isotypes, II or III, as well as mixtures of II and III, II and I&IV, or III and I&...