Neuroblastomain children develops in the immature nerve tissues that form the sympathetic nervous system. It usually affects the adrenal glands inside the abdomen. The disease is common in babies and children under the age of 5. Sarcomais a cancer that develops in the bone or sof...
Cancer and cardiovascular diseases (CVDs) share many of the same risk factors. Using a cloud-based health care database, we identified patients with malignancies that often require cardiotoxic treatments (leukemia/lymphoma and lung, breast, colon, renal, and head and neck cancers). We report the...
Have a family history of thyroid problems. Have pernicious anemia, type 1 diabetes, primary adrenal insufficiency, lupus, rheumatoid arthritis, Sjögren’s syndrome, or Turner syndrome. Take meds that have iodine. Are 60 or older. Had a previous thyroid condition or cancer (thyroidectomy or radi...
High DHEA levels on blood tests may be a sign of conditions such as congenital adrenal hyperplasia or cancer of the adrenal gland. Thyroid Hormones Thyroid function is determined by the levels of a group of hormones. These hormones are produced by the pituitary and thyroid glands. The three ...
Treatment depends on the type of PP: Long-acting GnRHa, either intramuscularly or implanted, is the norm of care for CPP management, while in PPP, especially in congenital adrenal hyperplasia, the goal of management is to suppress adrenal androgen secretion by glucocorticoids. In addition, ...
Thyroid cancer Thyroid cancer is far more common among adult women than men or youth. About 2/3 of cases occur in people under age 55. There are different kinds of thyroid cancer, depending upon the specific cell type within the thyroid that has become cancerous. Most cases of thyroid canc...
Cancer sequencing studies have primarily identified cancer driver genes by the accumulation of protein-altering mutations. An improved method would be annotation independent, sensitive to unknown distributions of functions within proteins and inclusive of noncoding drivers. We employed density-based clustering...
this type of data, even though available for large cohorts, does not allow formal testing of all criteria defining chromothripsis for a conclusive identification of bona fide chromothriptic cases3. In the second study, Gröbner and colleagues analysed chromothripsis in paediatric cancer14, focusing ...
after it forms, it is a very life-threatening cancer and one of the most difficult cancers to treat. While lung cancer can spread to any organ in the body, certain locations -- particularly the adrenal glands,liver, brain, and bones -- are the most common sites for lung cancer ...
If needed, adenomas can often be removed with surgery. Although not common, this type of tumor can become malignant. In the colon, less than 1 out of every 10 adenomas become cancerous. Fibromas (orfibroids)are tumors of fibrous or connective tissue that can grow in any organ. Fibroids co...