Diabetes Type 1: One Step Closer to a Cure.Interviews physician Camillo Ricordi, director of the University of Miami School of Medicine's Diabetes Research Institute, regarding an experimental treatment for type 1 diabetes.EBSCO_AspMedical Update...
摘要: Type one diabetes (T1D) is a complex T cell-mediated autoimmune disease, the defining feature of which is the destruction of the insulin-secreting beta- (β)- cell. Both genetic and environmental f ...关键词:beta-cell cytokines immunoregulation regeneration T-cells ...
An in-depth knowledge of type 1 diabetes pathogenesis is critical to understanding how precision medicine may apply to type 1 diabetes. In the early 1930s it was noticed that people with diabetes responded differently to insulin, enabling the differentiation between insulin-insufficient and insulin-se...
Bridging this gap is one goal of the The Environmental Determinants of Diabetes in the Young (TEDDY) study, a prospective study that aims to identify environmental causes of T1D28. It includes six clinical research centres in the United States (Colorado, Georgia/Florida and Washington) and Europ...
In type 1 diabetes (T1D), immune-cell infiltration into the islets of Langerhans (insulitis) and β-cell decline occurs many years before diabetes clinically presents. Non-invasively detecting insulitis and β-cell decline would allow the diagnosis of ev
Blood glucose awareness training in Dutch type 1 diabetes patients: one-year follow-up. Neth J Med 2005;63:164-9, 2005.Broers S, Vliet KP, le Cessie S, Spinhoven PH, van der Ven NC, Radder JK: Blood glucose awareness ... S Broers,KPV Vliet,SL Cessie,... - 《Netherlands Journa...
The protocol has been divided in two main arms, one for patients with diabetes and another for healthy ones. In the following we provide details about enrollment, inclusion and exclusion criteria, and the protocol description. 3.2.1. Data collection and equipment Information collected at patient en...
But so often, living with type 2 diabetes (T2D) can make you feel physically and emotionally isolated. Not only can it be hard to do things you loved before your diagnosis, but it can also feel like no one understands what it’s like. ...
We are aimed to systematically assess the worldwide trend in incidence of childhood type 1 diabetes mellitus (CT1DM) from 1965 to 2012 and to discuss whether climate affect incidence of CT1DM. We searched the relevant literatures in detail to judge the effect of different climates on incidence...
calculating 2-sidedp-values and adjusting for multiple testing using BH correction. If significance was reached (*p < 0.05), log2 fold changes between NT1 patients and controls are shown on the right. Data derived from FACS-sorted CD4+ and CD8+ cells available from one NT1 patient were...