Recent research in neuroimmunology has revolutionized our understanding of the intricate interactions between the immune system and the central nervous system (CNS). The CNS, an “immune-privileged organ”, is now known to be intimately connected to the immune system through different cell types and...
Challenging the Paradigm: EGFR wild-type benefit from an EGFR inhibitor in NSCLCThis article describes the case of a patient treated at a Cancer Centre in Taiwan and at the British Columbia Cancer Agency in Canada. This patient experienced a remarkable response to a number of different systemic ...
A Lucas - 《Journal of Business & Economic Statistics》 被引量: 115发表: 2000年 Revealing the X/O Impedance Mismatch We take the term X/O impedance mismatch to describe the difficulty of the OO paradigm to accommodate XML processing by means of recasting it to typed OO programming. In part...
The type I interferon pathway has been implicated in the pathogenesis of a number of rheumatic diseases, including systemic lupus erythematosus, Sjögren syndrome, myositis, systemic sclerosis, and rheumatoid arthritis. In normal immune responses, type I interferons have a critical role in the defence...
While Na0.005Mg2.995Sb1.5Bi0.5 sample shows the highest average ZT of ∼0.29 in the temperature range of 300–773 K and matched thermal expansion behavior with the state-of-the-art n-type Mg3.2Sb1.5Bi0.49Te0.01Mn0.01, which is of great significance for practical applications. Taking the ...
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Most current scientists are specialists who know a lot about a tiny area of their field. They tend to publish of their research results in papers and books that are solely accessible for their close peers, in terms of concepts, ideas, language, goals and approaches. This approach used to be...
We summarize current knowledge on the structure of mating type loci in different species of basidiomycetes, giving special consideration to bipolar and tetrapolar heterothallic species. In all three subphyla of the Basidiomycota, heterothallic bipolar, h
A. The independent probabilistic firing of transcription factors: a paradigm for clonal variability in the zebrafish retina. Dev. Cell 34, 532–543 (2015). Article CAS PubMed PubMed Central Google Scholar McLaughlin, T. & O'Leary, D. D. Molecular gradients and development of retinotopic ...
Type 2 diabetes (T2D) and Clear-cell renal cell carcinoma (ccRCC) are both complicated diseases which incidence rates gradually increasing. Population based studies show that severity of ccRCC might be associated with T2D. However, so far, no researcher