Magnetic resonance imaging (MRI) can detect breast cancer in high-risk patients, but is associated with a significant false-positive rate resulting in unnecessary breast biopsies. More data are needed to define the role of MRI screening for specific high-risk groups. We describe our experience ...
Conclusion: The presence of a high anti-HER2Th1 response is superior to pMRI for the assessment of pCR in HER2(+)BC. This assay has considerable promise, and validation in a large-scale study is warranted. 展开 关键词: Breast Cancer Negative Predictive Value Invasive Lobular Carcinoma Index ...
Analyses of circulating tumor cells have been shown to be effective for the detection of cancer relapse and prognosis prediction. However, research regarding its utility in sarcoma remains scarce. In this study, the microfluidic chip-type cell sorter On-chip Sort was used to construct a system fo...
Diffuse-type gastric cancer (DGC) exhibits rapid disease progression and a poor prognosis. There are no effective serum biomarkers for early detection of DGC. We have established an E-cadherin/p53 double conditional knockout (DCKO) mouse line that recapi
Cancer of the breast along with neuroendocrine distinction: the up-date using the Posted onDecember 20, 2024 Reply Moreover, some appendiceal tumors may show a cecal protuberance. Here, we report an uncommon case of appendiceal cancer with an SMT-like cyst, that has been a protuberant lesion...
Evaluation of inadequate, indeterminate, false-negative and false-positive cases in cytological examination for breast cancer according to histological type Background We previously investigated the current status of breast cytology cancer screening at seven institutes in our area of southern Fukuoka Prefectu...
insulitis is presentin patientsfor many years before T1D diagnosis. Biopsies obtained at the time of diagnosis in T1D subjects exhibit atrophy prevalently in the tail of the pancreas, where the β-cell mass is severely diminished, despite the other cells (such as α and δ cells) ...
The MEN1 gene is a tumor suppressor gene, and mutations in it account for the development of the MEN1 clinical syndrome through impair- ment of several cell functions, such as cell proliferations, cell growth control, apoptosis, DNA replication and repair, gene expression, transcriptional ...
MRI scans and a machine learning program were used to calculate brain age and quantify Alzheimer's disease like atrophy. Alzheimer disease–like regional atrophy was comparable between the groups and not explicitly associated with either group. Other regions with atrophy in EDIC participants were obse...
Garcia-Ibilcieta, et al., “Simple method for production of randomized human tenth fibronectin domain III libraries for use in combinatorial screening procedures,” Bio Technologies, 44: 559-562 (2008). Van den Burg et al., “Selection of mutations for increased protein stability”, Curr. Op...