Hence, the absorption and solubility of the drug are two major factors for oral administration. All of the 3-substituted-4-(quinoxalin-6-yl) pyrazoles 19a–d showed good intestinal absorption. All compounds showed low or very low aqueous solubility at room temperature. However, the structure ...
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The experimental results provide a reference for the design of multi-nozzle bits for many applications such as radial jet drilling (RJD) and bent pipe cleaning. Keywords: coalbed methane (CBM) drainage; tree-type drilling; water jet; multi-nozzle bits; rock-breaking properties 1. Introduction ...