Importantly, the cellular composition of individual neuronal subtypes in these regions substantially differs from previously well-profiled cortical and hippocampal regions (Saunders et al., 2018; Zeisel et al., 2018). For example, the NAc contains dopaminoceptive populations of GABAergic medium spiny...
The composition of the BlueTYPE RT-qPCR reactions with the different FAM- and HEX-labelled assay(s) per well was 1.0 μl (0 μl, if two serotype-specific assays were combined in one well) of RNase-free water, 6.25 μl of 2x RT-PCR buffer, 0.5 μl of RT-PCR Enzyme...
termed as “cell deconvolution” within the context of cell biology. The estimation of cell type-specific gene expression is a well established and challenging problem in the field. Prior work includes but is not limited to TAPE [5], bMIND [6], BayesPrism [7], and...
但 Ikarus 僅僅是用於把活字數碼化,其軟件設計的理念並沒有 Metafont 那樣超前。 Knuth 本人也承認: Asking an artist to become enough of a mathematician to understand how to write a font with 60 parameters is too much.(要讓一個藝術家成為一個數學家,然後編寫一個帶有60個參數的字體,...
Robert Slimbach 与 Carol Twombly。图:Tumblr 这样,Adobe 提供字体设计、字体使用、文档排版和打印机输出的一整套技术规范,Aldus 专注于排版设计软件的开发,而苹果则以 Mac 电脑为基础,把这些技术带给千千万万的普通民众。古老、缓慢、昂贵的活字和照相排版,正在被更为廉价、方便的计算机代替。桌上出版的燎原之火,从...
A positive-feedback loop between tumour infiltrating activated Treg cells and type 2-skewed macrophages is essential for progression of laryngeal squamous cell carcinoma Wei Sun, Fan-Qin Wei, Wei-Jin Li, Jia-Wei Wei, Hua Zhong, Yi-Hui Wen, Wen-Bin Lei, Lin Chen, Hang Li, ...
16, 17 Lysosomal storage occurs in cells from every tissue and organ of patients with MLIV.4, 16, 17, 18, 19, 20, 21 The composition of the stored material varies from tissue to tissue,21 is heterogeneous, and includes sphingolipids (mostly gangliosides), phospholipids, and acid ...
However, many T4SSs also display striking differences in subunit composition and number compared to the ‘archetypal’ VirB/VirD4 T4SS and related systems. Many Gram-positive conjugation systems, for example, are composed of only a subset of the VirB/VirD4 homologs [15], [16], whereas other...
5298018 Method for treating cardiovascular disease through adjunctive photodynamic therapy 1994-03-29 Narcisco, Jr. 5292331 Endovascular support device 1994-03-08 Boneau 5264581 Radioiodinated angiotensin receptor antagonists 1993-11-23 Carini 5256687 Pharmaceutical composition for the treatment of high bl...
Lysozymes are enzymes that lyse bacterial cell walls, an activity widely used for host defense but also modified in some instances for digestion. The biochemical and evolutionary changes between these different functional forms has been well-studied in t