Nicholas Bagnall
Meiosis is the specialized cell division during which parental genomes recombine to create genotypically unique gametes. Despite its importance, mammalian meiosis cannot be studied in vitro, greatly limiting mechanistic studies. In vivo, meiocytes progress asynchronously through meiosis and therefore the ...
we created two gRNAs introducing a genomic deletion in theNITRATE REDUCTASE1(NIA1, AT1G77760) gene. NIA1 is one of twoArabidopsisnitrate reductase enzymes converting nitrate (NO3) to ammonium (NH4) and on NH4-deficient mediumnia1mutants develop a clearly visible phenotype...
genetic perturbations, drug treatments, and disease states. Computational tools for rigorous assessment of cell type-specific loops across multiple biological conditions are needed. We present 3DeFDR, a simple and effective statistical tool for classifying...
Only cells with "excitable membranes" can create action potentials. The two types of cells in the body that can do this are? Both internal and external structure of a cell reflects its function. What type of organelle...
We created a novel glc7 catalytic mutant (glc7-E101Q). Phenotypic analysis indicates that this novel allele exhibits slow growth and defects in glucose metabolism but normal cell cycle progression and chromosome segregation. This suggests that glc7-E101Q is a hypomorphic glc7 mutant. Synthetic ...
We created a novel glc7 catalytic mutant (glc7-E101Q). Phenotypic analysis indicates that this novel allele exhibits slow growth and defects in glucose metabolism but normal cell cycle progression and chromosome segregation. This suggests that glc7-E101Q is a hypomorphic glc7 mutant. Synthetic ...
However, the silencing activity of the FNIII domain mutant was weaker than that of the ATF7IP WT, and some of the de-repressed germ cell-related genes in Atf7ip KO mESCs were not silenced by the FNIII domain mutant. Such germ cell-related genes are targeted and silenced by the MAX/...
of Fungi: Interaction with the EnvironmentBiological, Biochemical and Molecular Interactions between Entomopathogenic Fungi and Their HostsBiology of Saccharomyces cerevisiae and Mechanisms of Interaction with the HostBreeding and Metabolism of Edible FungiCandida and CandidiasisCandida aurisCell Adhesion in ...
Haplotype analysis has shown that mutations occur more frequently in male meiosis. Even though the disease is almost reported in males, rare sporadic cases in females do occur. Affected females generally have low levels of IDS activity associated with a mild clinical phenotype. The result of ...