In Vibrio cholerae, the Type IV pilus (T4P) is thought to mediate DNA uptake by binding DNA and retracting back toward the cell. How the DNA enters the periplasm is unclear. One hypothesis suggests that the DNA-bound T4P retracts completely so that the DNA would pass through the outer ...
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PilM/N/O/P proteins form an inner membrane complex that affects the stability of the Pseudomonas aeruginosa type IV pilus secretin J. Mol. Biol., 394 (2009), pp. 128-142 View PDFView articleView in ScopusGoogle Scholar 46 Abendroth J., Kreger A.C., Hol W.G. The dimer formed by th...
Interactions between the lipoprotein PilP and the secretin PilQ in Neisseria meningitidis. J Bacteriol. 2007;189(15):5716–27. https://doi.org/10.1128/JB.00060-07. Article CAS PubMed PubMed Central Google Scholar Varga JJ, Therit B, Melville SB. Type IV pili and the CcpA protein are ...
Interactions between the lipoprotein PilP and the secretin PilQ in Neisseria meningitidis. J Bacteriol. 2007;189(15):5716–27. https://doi.org/10.1128/JB.00060-07. Article CAS PubMed PubMed Central Google Scholar Varga JJ, Therit B, Melville SB. Type IV pili and the CcpA protein are ...
type IV pilus (‘wide’ and ‘narrow’), differing in structure and protein composition. Wide pili are composed of the major pilin PilA4, while narrow pili are composed of a so-far uncharacterized pilin which we name PilA5. Functional experiments indicate that PilA4 is required for natural...
Eisenbrandt, R. et al. Conjugative pili of IncP plasmids, and the Ti plasmid T pilus are composed of cyclic subunits.J. Biol. Chem.274, 22548–22555 (1999).Provides evidence that the pilin subunits of theA. tumefaciensVirB/D4 and the plasmid RP4 Tra systems undergo head-to-tail cycliza...
Here we uncovered a sequential, outside-in assembly pathway starting with the outer membrane (OM) PilQ secretin, and proceeding inwards over the periplasm and inner membrane (IM) to the cytoplasm. Specifically, by taking advantage of the cell biology tools for studying T4P in M. xanthus, we...
This machine involves a secretin in the outer membrane and a dynamic short pilus that functions as a piston. Type IV pili Type IV pili are retractable pili involved in adherence and motility and found on diverse bacteria. They are related to the piston of the type II secretion apparatus. ...
salmonicida: the type three secretion system (T3SS) encoded on a large plasmid and described for the first time in the Aeromonas genus in our laboratory ten years ago [2, 3]; the surface layer protein VapA [4]; a type I pilus [5]; three type IV pilus systems [6, 7]; superoxide ...