Carbonnelle, E.; Helaine, S.; Prouvensier, L.; Nassif, X.; Pelicic, V. Type IV pilus biogenesis in Neisseria meningitidis: PilW is involved in a step occurring after pilus assembly, essential for fibre stability and function. Mol. Microbiol. 2005, 55, 54-64....
A method that enables low-resolution 3D imaging of intact type IV pilus machines within the bacterial envelope by selecting and averaging multiple volumes within a full tomogram (subtomograms) that each represent the same protein, revealing the electron density of individual components. ...
Type IV pili are filamentous nanomachines that exemplify such bacterial surface structures1,2. Typically, the type IV pili are helical polymers constituted of one protein component, the major pilin. The assembly and disassembly of the major pilin leads to rapid pilus extension and retraction within...
Protein functionProtein domain (COG, pfam)Type II secretion protein in:Type IV pilus protein (gene name or accession no.) in: Escherichia coli K-12Klebsiella oxytocaPseudomonas aeruginosaClostridium perfringensStreptococcus sanguis 2908Paenibacillus thiaminolyticus Mbale1 Pilus assembly ATPase COG2804, PF...
antivirulence PilB ATPase type IV pilus T4P assembly high-throughput screen benserazide levodopa INTRODUCTION The bacterial type IV pilus (T4P), an extracellular protein filament (1–5), is one of the most critical and prevalent structures or components essential for the pathogenesis of bacterial pa...
(1995) Rapid disrup- tion of epithelial barrier function by Salmo- nella typhimurium is associated with struc- tural modification of intercellular junctions. Infect. Immun. 63: 356-359. 30. Meyer TF, Billyard E, Haas R, Storzbach S, So M. (1984) Pilus sequences of Neisseria gonorrhoeae: ...
conjugation is mediated by a large transport apparatus—the conjugative type IV secretion system (T4SS)—produced by the donor cell and embedded in both its outer and inner membranes. The T4SS also elaborates a long extracellular filament—the conjugative pilus—that is essential for DNA transfer...
syringae is accomplished by fimbriae and exopolysaccharides [19, 20] genes which can be further distinguished in the GO with the terms "GO:0043683 type IV pilus biogenesis" and "GO:0045226 extracellular polysaccharide biosynthetic process", respectively. Conversely, "GO:0001907 killing by symbiont ...
salmonicida: the type three secretion system (T3SS) encoded on a large plasmid and described for the first time in the Aeromonas genus in our laboratory ten years ago [2, 3]; the surface layer protein VapA [4]; a type I pilus [5]; three type IV pilus systems [6, 7]; superoxide ...
Type IV pilus (T4P) protein filaments are important in Vibrionaceae family pathogenicity because they mediate natural transformation, adhesion, biofilm formation, and colonization of their hosts15,16,17,18,19,20. The genomes of V. cholerae, V. parahaemolyticus, and V. vulnificus all contain ...