Microbiology The Pseudomonas aeruginosa Type IV pilus-associated protein PilY1 is required for stable fiber formation and host attachment THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL Matthew Wolfgang HeinigerRyan WilliamPseudomonas aeruginosa is an opportunistic bacterial pathogen that is a leading cause...
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Mol. Cell. 11, 1139–1150 (2003). Describes the first type IVb pilin structure for V. cholerae TcpA, which reveals a new protein fold, together ...
Type IV pilus biogenesis and motility in the cyanobacterium Synechocystis sp. PCC6803 inactivation of pilD (encoding the leader peptidase) or pilC (encoding a protein required for pilus assembly) abolishes cell motility, and both pilus morph... D Bhaya,NR Bianco,D Bryant,... - 《Molecular Mi...
A method that enables low-resolution 3D imaging of intact type IV pilus machines within the bacterial envelope by selecting and averaging multiple volumes within a full tomogram (subtomograms) that each represent the same protein, revealing the electron density of individual components. ...
Protein functionProtein domain (COG, pfam)Type II secretion protein in:Type IV pilus protein (gene name or accession no.) in: Escherichia coli K-12Klebsiella oxytocaPseudomonas aeruginosaClostridium perfringensStreptococcus sanguis 2908Paenibacillus thiaminolyticus Mbale1 Pilus assembly ATPase COG2804, PF...
PilB is an ATPase responsible for providing energy for pilus assembly [11, 12]. PilC (described as the gene encoding the inner membrane core protein) is usually paired with pilB [11, 12]. It is speculated that there may be some unknown interactions between PilC and pilB [10]. PilT ...
The type IV pilus assembly complex: biogenic interactions among the bundle-forming pilus proteins of enteropathogenic Escherichia coli J. Bacteriol., 184 (2002), pp. 3457-3465 View in ScopusGoogle Scholar 23 Anantha R.P., Stone K.D., Donnenberg M.S. Effects of bfp mutations on biogenesis ...
PilB is an ATPase responsible for providing energy for pilus assembly [11, 12]. PilC (described as the gene encoding the inner membrane core protein) is usually paired with pilB [11, 12]. It is speculated that there may be some unknown interactions between PilC and pilB [10]. PilT ...
To explore the possibility that the PulG precursor could form a pilus-like structure, the PulG sequence was altered in a variety of ways, including (i) replacement of the characteristic hydrophobic region, which is required for the assembly of type IV pilins by the MalE signal peptide, or (...
The type IV pili are long filamentous organelles comprised of thousands of copies of the pilin subunit. The long term objective of this work is to understand the molecular assembly mechanism of this virulence factor by solving the x-ray crystal structures of type IV pilins and the pilus ...