Type IV pili (Tfp) represent such a structure: 6-nm-wide retractable filamentous appendages found in many bacteria, including human pathogens. Whereas the structure of Neisseria gonorrhoeae Tfp has been defined by conventional structural techniques, it remains difficult to explain the wide spectrum of...
Type IV pili (Tfp) represent such a structure: 6-nm-wide retractable filamentous appendages found in many bacteria, including human pathogens. Whereas the structure of Neisseria gonorrhoeae Tfp has been defined by conventional structural techniques, it remains difficult to explain the wide spectrum of...
Type IV pili (Tfp) are the most widespread appendages emanating from the bacterial cell envelope and protruding out to the extracellular environment. They participate in adhesion, cell–cell interactions, autoaggregation, DNA exchange and motility. Tfp consist of oligomerized pilin subunits assembled ...
Chuandong Wang1, Renate Lux2, Yuezhong Li1, Gerard C. L. Wong3 & Wenyuan Shi2 Myxococcus xanthus performs coordinated social motility of cell groups through the extension and retraction of type IV pili (TFP) on solid surfaces, which requires both TFP and exopolysaccharides (...
The majority of well- studied examples are represented by pathogens, and includes the requirement of functional flagella and/ or type IV pili (TFP) for pathogen colonization of the animal gut, human lung and plant leaf-surface (Haefele and Lindow, 1987; Nachamkin et al., 1993; Wassenaar et...
SummaryThe functionally versatile type IV pili (Tfp) are one of the most widespread virulence factors in bacteria. However, despite generating much research interest for decades, the molecular mechanisms underpinning the various aspects of Tfp biology remain poorly understood, mainly because of the comp...
PullingTogetherwithTypeIVPili 系统标签: pilipullingtypehenrichsenproteobacteriatfp JMolMicrobiolBiotechnol2004;7:52–62 DOI:10.1159/000077869 PullingTogetherwithTypeIVPili EricNudlemanDaleKaiser StanfordUniversity,DepartmentsofBiochemistryandofDevelopmentalBiology,Stanford,Calif.,USA DaleKaiser DepartmentofBiochemistryand...
Type IV pili (TFP)2 form the most widely distributed group, particularly prevalent in Proteobacteria, including major human pathogens such as Neisseria meningitidis and Pseudomonas aeruginosa (2, 3). TFP harbor tip adhesins which mediate cellular attachment to host tissue receptors (4), play a ...
摘要: Bacterialiofilmsreulticellularurface-boundommunities with importantumanealth impacts (1).or Pseudomonaseruginosa,iofilm-forming pathogenesponsibleor lethal infections inysticibrosis (2),heotilityppendagesype IV pili (TFP)ediatehe \"twitching\"otilityodebserved iniofilms (3)....
This process is mediated by Type IV pili (Tfp) (4-9). In addition, by powering a form of cell locomotion, reported as twitching motility (10), Tfp lead to the spread of the bacteria on the surface of the cells and the formation of microcolonies. Subsequent to the formation of these ...