Type IV collagen: A network for development differentiation, and disease. Adv Dev Biol 2005;Harvey SJ, Thorner PS: Type IV collagen: A network for development, differentiation, and disease. In Extracellular matrix in development and disease, vol. 15 . Edited by Miner JH. Amsterdam; Boston: ...
Collagen Type Ⅳ(Ⅳ型胶原抗体) 广州健仑生物科技有限公司 Collagen Type IV 是基底膜的主要成分。正常组织CollagenType IV 存在于间质和上皮的基底膜。该抗体可用于各种良恶性肿瘤组织中基底膜分布的研究,也可用于研究血管外皮细胞瘤,血管肉瘤、血管内皮瘤这类血管源性肿瘤。 我司还提供其它进口或国产试剂盒:登革热...
Jay C.Jha, ...Mark E.Cooper, inAdvances in Chronic Kidney Disease, 2014 Collagen Type IV Collagen type IV, a high-molecular-weight protein (∼540 kDa), is the main constituent of glomerular andtubular basement membranesas well as the mesangial matrix. It has been found to be increased ...
A new genome-wide association study of patients with type 1 diabetes mellitus reveals novel loci that are associated with the development of diabetic kidney disease. The most significant of these loci encodes the 伪3 chain of type IV collagen, which is an important component of the glomerular ...
Hereditary type IV collagen diseases: Alport syndrome and benign familial hematuria Alport syndrome (AS) is a hereditary nephropathy, characterized by hematuria progressing to end stage renal failure (ESRF), hearing loss and ocular lesions. Numerous mutations in the COL4A5 gene encoding the α5-chai...
Rheumatic disease sera were examined by a sensitive and specific enzyme linked immunosorbent assay (ELISA) for antibodies to native and to denatured type IV collagen from basement membranes of bovine anterior lens capsules or human placenta. The frequency of antitype IV collagen antibodies depended on...
Chemotaxis and haptotaxis of human malignant mesothelioma cells: effects of fibronectin, laminin, type IV collagen, and an autocrine motility factor-like s... A human malignant pleural mesothelioma cell line (STAV) was studied with respect to production of the extracellular matrix components laminin,...
In the mandibular condylar cartilage (MCC), the PCM is comprised primarily of type VI collagen, type IV collagen, and laminin7. The chondrocyte anchors to type VI collagen8 through β1-integrin and neuron-glia antigen 2 (NG2), also known as Chondroitin Sulfate Proteoglycan 4 (CSPG4)9,10...
Alport syndrome is a progressive hereditary kidney disease characterized by hematuria, sensorineural hearing loss an... Kar ryvason,Jn Zhou,Srkkasa Hoskka,... - 《Kidney International》 被引量: 307发表: 1993年 Structure of the human type IV collagen gene COL4A3 and mutations in autosomal ...
Mutations in both alleles of the autosomal type IV collagen genes, or hemizygous mutations in the X-linked gene encoding the alpha 5 chain of type IV collagen, result in progressive renal disease that is often associated with sensorineural deafness (Alport syndrome). Animal models of Alport ...