Verkoczy LK,Marsden PA,Berinstein NL.hBRAG a novel B cell lineage cDNA encoding a type II transmembrane glycoprotein potentially involved in the regulation of recombination activating gene 1 (RAG1).European Journal of Immunology. 1998Verkoczy LK,Marsden PA,Berinstein NL.hBRAG a novel B cell ...
We conclude that the Joro 177 MoAb recognizes the heavy chain of the mouse CD98 type II transmembrane glycoprotein. DISCUSSION In our search for cell membrane proteins expressed on PHSC and/or very early hematopoietic progenitor cells, we found that the Joro 177 cell surface antigen was expressed...
However, the development of CAII-positive type I/II oligodendrocytes in the spinal cord and molecules that regulate their development have not been elucidated yet. Teneurin-4 (Ten-4), a type II transmembrane glycoprotein, has been identified as a regulator of myelination of small diameter axon...
For example, NCI-H460 tumour cells actively release MVs containing EMMPRIN, a transmembrane glycoprotein highly expressed by tumour cells, MV-encapsulated EMMPRIN that facilitates tumour invasion and metastasis via stimulating matrix metalloproteinase expression in fibroblasts3. Tumour cell exosomes also ...
TMPRSS2 (transmembrane serine proteinase 2) is a multidomain type II transmembrane serine protease that cleaves the surface glycoprotein HA (haemagglutinin) of influenza viruses with a monobasic cleavage site, which is a prerequisite for virus fusion and propagation. Furthermore, it activates the fusi...
A biochemical characterization of p180 showed it to be a transmembrane glycoprotein with an extracellular domain, which consists of approximately 30 kDa of complex oligosaccharides attached to at least 45 kDa of the protein core. The cytoplasmic domain of p180 was found to contain a serine residue(...
Hpx, hemopexin-like domain; TM, transmembrane domain. MT1-MMP has also been shown to activate proMMP-13 on the cell surface [44]. TIMP-2 is not involved in this activation, but the hemopexin domain of MMP-13 is essential [45]. However, the detailed mechanism is not clearly understood....
Royant A, Nollert P, Edman K, Neutze R, Landau EM, Pebay-Peyroula E (2001) X-ray structure of sensory rhodopsin II at 2.1-Å resolution. Proc Natl Acad Sci USA 98:10131–10136 (PDB id 1H68) CASPubMedGoogle Scholar Saier MH Jr (2000) Families of proteins forming transmembrane ch...
Transmembrane Gate Movements in the Type II ATP-binding Cassette (ABC) Importer BtuCD-F during Nucleotide Cycle ATP-binding cassette (ABC) transporters are ubiquitous integral membrane proteins that translocate substrates across cell membranes. The alternating access... B Joseph,G Jeschke,BA Goetz,....
FGF21 exerts its metabolic regulation in adipocytes by binding to its receptor FGFR1 and co-receptor KLB, the latter of which is a single transmembrane glycoprotein that determines the tissue specificity of FGF21 actions (Fisher and Maratos-Flier, 2016). To interrogate whether the actions of FGF...