Type I neurones have somewhat elongated cell body, which is greater than 12 om in diameter. Both the cell body and the processes possess thick myelin cover. Type II spiral ganglion cells are, in turn, relatively few in number, their round cell body is smaller than 12 om in diameter, ...
To cause peripheral damage, we used a noise-induced hearing loss (NIHL) paradigm. Mice were bilaterally exposed to an octave band (8–16 kHz) noise at 100 dB SPL for 2 h (Fig.1a, b). To assess the consequences of this noise exposure on peripheral structures, we measured and quant...
SGN spiral ganglion neuron TEM transmission electron microscopy type I ganglion cells large afferent neurons innervating inner hair cell type II ganglion cells small afferent neurons innervating outer hair cells Key words human cochlea spiral ganglion neurons non-myelinated Schwann cells laminin-β2 colla...
SGN spiral ganglion neuron TEM transmission electron microscopy type I ganglion cells large afferent neurons innervating inner hair cell type II ganglion cells small afferent neurons innervating outer hair cells Key words human cochlea spiral ganglion neurons non-myelinated Schwann cells laminin-β2 colla...
Quantification was carried out using Zen software (Zeiss) and Photoshop CS6 (Adobe). Quantification of spiral ganglion neuron numbers in each cochlear turn was performed as described previously12. Supplementary Video was made using syGlass system from IstoVisio Inc. (https://www.syglass.io/)....
(C)Cep250transcript expression in the spiral ganglion neuron at different ages.Calb2,Calb1, andLypd1are markers for type I, II, and III neurons, respectively. SGN, spiral ganglion neuron. (D,E) Immunohistochemistry was performed for wildtype andCep250knockout mice (P30). Cep250 (red) was...
Metformin attenuates cadmium-induced 该研究采用脓毒症模型研究的"金标准"CLP 来诱导脓 degeneration of spiral ganglion neuron via restoring autophagic flux in 毒症小鼠心肌损伤,模拟临床上消化道穿孔所诱导的脓毒症 primary culture. J Inorg Biochem. 2022;234:111901. 心肌损伤,探讨二甲双胍诱导自噬对脓毒症...
Anniko M (1983). Early development and maturation of the spiral ganglion. Acta Otolaryngol 95, 263–276. Baird RA, Desmadryl G, Fernandez C & Goldberg JM (1988). The vestibular nerve of the chinchilla. II. Relation between afferent response properties and peripheral innervation patterns in the...
spiral ganglion neuronapoptosiscytochrome ccaspase 3PARPcalcineurinApplication of ouabain to the intact round-window (RW) membrane of the gerbil cochlea induces apoptosis in most spiral ganglion neurons (SGNs), leaving a few neurons intact (Schmiedt et al. 2002 ). Here, physiological measures and ...
Convergence of Type 1 Spiral Ganglion Neuron Subtypes onto Principal Neurons of the Anteroventral Cochlear Nucleusbushy cellcochlear nucleusendbulb of Heldspiral ganglionT-stellate cellThe mammalian auditory system encodes sounds with subtypes of spiral ganglion neurons (SGNs)...