Type I (insulin dependent) diabetes: a disease of slow clinical onset? Br Med J (Clin Res Ed) 1987;294:342-345Tarn AC, Smith CP, Spencer KM, Bottazzo GF, Gale EAM (1987) Type 1 (insulin-dependent) diabetes: a disease of slow clinical onset? Br Med J 294: 342–345...
Following the seminal discovery of insulin a century ago, treatment of individuals with type 1 diabetes (T1D) has been largely restricted to efforts to monitor and treat metabolic glucose dysregulation. The recent regulatory approval of the first immunotherapy that targets T cells as a means to de...
Late-onset type 1diabetes symptoms More research is being done on what's calledLatent Autoimmune Diabetes in Adults(LADA). Some people refer to this as "Diabetes 1.5" or "Diabetes 1 1/2" because it overlaps with parts of both type 1 and type 2 diabetes. LADA symptomscan come on very s...
Type 1 diabetes, a chronic condition affecting millions of young individuals globally, is not exclusive to childhood. As many as half of all cases are diagnosed during adulthood, and there is a need to understand the factors contributing to the development of type 1 diabetes in adults. Ad A ...
type I diabetes- severe diabetes mellitus with an early onset; characterized by polyuria and excessive thirst and increased appetite and weight loss and episodic ketoacidosis; diet and insulin injections are required to control the disease autoimmune diabetes,growth-onset diabetes,IDDM,insulin-dependent ...
has been strongly suggested as a causative factor in the initiation of Type I Diabetes. Genetic factors may also have a role to play in this alteration of the immunity. Type 1 diabetes also appears to be triggered by some viral infections or less likely stress-related or environmental factors...
cells first fail to recognize and clear out. As a result, these cells accumulate and spread so widely within the pancreas that by the time the immune system eventually recognizes the problem, it essentially has to raze the whole insulin-producing system, leading to the onset of diabetes. ...
de Goffau, M. C. et al. Aberrant gut microbiota composition at the onset of type 1 diabetes in young children.Diabetologia57, 1569–1577 (2014). ArticleGoogle Scholar de Goffau, M. C. et al. Fecal microbiota composition differs between children with β-cell autoimmunity and those without....
Low vitamin D levels have been reported in multiple immune disorders such as type 1 diabetes mellitus (T1DM). The purpose of our study was to determine vit
The type and the position of HNF1A mutation modulate age at diagnosis of diabetes in patients with maturity-onset diabetes of the young (MODY)-3. The clinical expression of maturity-onset diabetes of the young (MODY)-3 is highly variable. This may be due to environmental and/or genetic fact...