This chapter focuses on the structure and biosynthesis of type I collagen and discusses how cytokines, hormones, and growth factors regulate its synthesis. Type I collagen is the most abundant extracellular protein of bones and it is essential for bone strength. Each molecule of type I collagen ...
细胞培养级猪I型胶原 Cell Culture Grade Porcine Type I Collagen Cat#1203 胶原蛋白是脊椎动物体内丰富的蛋白质,存在于皮肤、软骨、骨、椎间盘、血管、肌腱、韧带和角膜中,是细胞外基质(ECM)的主要成分。I型胶原由两条相同的α1链和一条不同的α2链(1)组成,形成称为原胶原的三螺旋结构。这种三螺旋构象增加...
Type IV collagens are composed of α1(IV) to α5(IV) and are found in the basement membranes of various tissues. Unlike collagen types I, II, III, V, and XI, which are fibrillar, type IV collagen is not fibrillar in structure. The synthesis of collagens in cultured cells has aided...
Type I Collagen is the most abundant type of collagen in the human body and is a major structural protein prevalent in skin, bone, tendon, and other fibrous connective tissues. All collagens are characterized by a secondary protein structure consisting of three polypeptide chains wrapped around on...
type I collagen. As mentioned above, aging is accompanied by changes in molecular organization of type I collagen, and consequently the biomechanical properties. Several studies have used PRS to characterize the anisotropic response of collagen in tendon15,16, to investigate the structure and ...
Collagen Detection The extracellular matrix (ECM) is a highly dynamic and complex three-dimensional structure composed of a macromolecule network including collagen, glycosaminoglycans (GAGs), elastin, fibronectin, and several other non-cellular structures. The purpose of the ECM is to provide a ...
(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described. This recombinant mini pro-alpha 1(I) collagen consists of a shortened alpha 1(I) chain with following domain structure from N- to C-terminus: N-propeptide, N‑telopeptide, the 33 ...
Here we present a crystallographic determination of the collagen type I supermolecular structure, where the molecular conformation of each collagen segment found within the naturally occurring crystallographic unit cell has been defined (P1, a ≈ 40.0 , b ≈ 27.0 , c ≈ 678 , α≈ 89.2°, β...
collagen type V and four proteoglycans: three with keratan sufate chains; lumican, keratocan, osteoglycin and one with a chondroitin sulfate chain; decorin... JR Hassell,DE Birk - 《Experimental Eye Research》 被引量: 467发表: 2010年 Primary structure of the human heparan sulfate proteoglycan ...
2015-02-26上传 新型胶原支架材料的结构特征与性能 properties and structure characterization of new type collagen scaffold materials 文档格式: .pdf 文档大小: 277.24K 文档页数: 5页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: ...