The alveolar epithelium is composed of alveolar type 1 (AT1) and alveolar type 2 (AT2) cells, which represent approximately 95% and approximately 5% of the alveolar surface area, respectively. Lung liquid clearance is driven by the osmotic gradient generated by the Na,K-ATPase. AT2 cells have...
GENERATION OF ALVEOLAR EPITHELIAL TYPE 1 (AT1) CELLSThe technology described herein is directed to methods of producing or differentiating AT1 cells, and AT1 cells made by the methods described herein.
Type I alveolar epithelial cells These cells have few cytoplasmic organelles but are remarkable for their attenuated cytoplasm, which extends long distances from the nuclear zone of the cell (seeFigs 1.27 and 1.28) and may even penetrate the alveolar wall so that one cell contributes to the linin...
Answer to: Type I alveolar cells ___. (a) secrete surfactant (b) are squamous epithelial cells (c) are macrophages (d) function mainly in the...
Alveolar type II (ATII) cells inhibit fibroblast proliferation in coculture by releasing or secreting a factor(s) that stimulates fibroblast production of prostaglandin E2 (PGE2). In the present study, we sought to determine the factors released from ATII cells that stimulate PGE2 production in fib...
In this chapter we will briefly review the techniques available for isolation and culture of type II pneumocytes and describe in detail a technique for the rapid isolation of adult rat type II cells.doi:10.1007/978-3-0348-8855-4_15J. S. Lwebuga-Mukasa...
Rat alveolar type I cells proliferate, express OCT-4, and exhibit phenotypic plasticity in vitro. Am J Physiol Lung Cell Mol Physiol 2009.Gonzalez, R.F., Allen, L., and Dobbs, L.G. Rat alveolar type I cells proliferate, express OCT-4, and exhibit phenotypic plasticity in vitro. Am J...
Alveolar type II cells that were isolated from organotypic cultures of fetal rat lung and maintained in primary monolayer culture were analyzed. Morphologically the cells retained many characteristics of type II cells in vivo. Biochemical analysis revealed that the cells contained and synthesized phosphati...
产品名称: Human-Normal-Alveolar-Cells-Type-1 产品型号: 产品展商: ABM产品文档: 无相关文档 简单介绍 Human-Normal-Alveolar-Cells-Type-1Human-Normal-Alveolar-Cells-Type-1 的详细介绍 Print Version Description Type I alveolar epithelial cells extend across several air sacs and cover more than 95% of...
The regulation of cell cycle control in alveolar epithelial type II cells (AEC2) in response to peptide growth factors and extracellular matrix signals is not well understood. Herein, we have determined that, in adult rat AEC2 in primary culture on Engelbreth-Holm-Swarm biomatrix (Matrigel) ...