Type B lactic acidosis (LA) represents a rare and often lethal complication of haematological malignancy. Here, we present a case report of a patient who developed a type B lacticacidosis presumably due to concurrent chronic myelomonocytic leukaemia (CMML). The LA reached a peak of 21 mmol/L....
nausea or vomiting, weakness, and headache. You should avoid drinking large amounts of alcohol when taking this drug because it may trigger a rare side effect, a buildup of acid in your blood called lactic acidosis.
but it can also increase blood glucose levels. Many people with diabetes find that relaxation techniques can help manage their condition. Examples are visualization, meditation, or breathing exercises. Taking advantage of social support networks is also helpful, like talking with a relative...
Glycogen storage diseases are known to exist in dogs (usually miniature breed puppies), cats, horses, and primates, and are generally characterized by an inability to form or degrade glycogen in normal metabolic pathways. Examples are atype I von Gierke’s-like disease(a Glc-6-Pase deficiency...
we present a broad review of rare genetic forms of diabetes that have differing diagnostic and/or treatment implications from type 1 and type 2 diabetes. Advances in understanding the genotype-phenotype associations in these rare forms of diabetes offer clinically available examples of evolving precisio...
Patients with GSD I have significant lactic acidosis during episodes of hypo- glycemia with values that may be variable but that are usually 10 mmol/l or more. If there is a concern about blood lactate levels due to use of a tourniquet to obtain the blood sample, then examination of the ...
serum metformin is not routinely measured in most hospitals. MALA should be suspected in patients with lactic metabolic acidosis and in patients who have the following conditions: evidence of metformin ingestion; severe metabolic acidosis with pH ≤7.1; remarkably increased lactate concentration ≥15 mmo...
and wherein the components (A), (B) and the optionally existing component (C) are administered sequentially or separately. As already mentioned above examples of other anti-diabetic compounds useful in the pharmaceutical compositions, combination products and kits according to the invention are selecte...
Other examples include: Inhibitors of key enzymes involved in the hepatic glucose production and secretion (e.g., fructose-1,6-bisphosphatase inhibitors), and direct modulation of enzymes involved in insulin signaling (e.g., Protein Tyrosine Phosphatase-1B, or “PTP-1B”)....
He had persistently elevated serum lactate attributed to malignancy-associated type B lactic acidosis as a diagnosis of exclusion. As he remained clinically stable with a near-normal pH, his elevated lactate was not specifically treated. This patient had an unusual type B lactic acidosis associated ...