A popular method for ct-eQTL mapping is to assess the interaction between the genotype of a genetic locus and the abundance of a specific cell type using a linear model. However, this approach requires transforming RNA-seq count data, which distorts the relation between gene expression and ...
Helping someone grow and become a better person nearly defines what a psychotherapist does. Diplomats think in imaginative ways about "what might be". They are most likely to approach others with an "unconditional positive regard" - often a trait valued in these professions. Because of these ...
Overall, the level of knowledge to support the ideotype approach depends on the crop and final trait (e.g. disease resistant, end-use quality) considered. The initial ideotype of Donald was built for low- or non-stress environments where light capture was the major limitation to grain yield...
provides type-safe code inspection capabilities (a novelty in the field of statically-typed staging), it can be used to achieve quoted staged rewriting (QSR)[2], an approach to program optimization that mixes the advantages of user-defined rewrite rules, strategic program transformation and MSP....
and prefer structured teaching; holist learners learn in a top-down, hierarchical fashion; they approach learning as a whole, without breaking it down into smaller tasks; they usually work spontaneously; in order to process information, holists do not need structure, and can think broadly about ...
ISTP women tend to be very rational individuals with a results-oriented approach to life. They usually neglect their emotions while making decisions and rely on their analytical thinking patterns instead. As a result, ISTP females are often perceived as insensitive people who can’t deal with emot...
To our knowledge, this is the first approach to achieve systematic noncoding variant interpretation at cell type levels, which may substantially promote the understanding of biology underlying phenotype-causal genetic variation. The data generated in this study represents an important resource. We ...
Direct Approach 更符合Spark的思维。...在调用该方法时,会先创建 val kc = new KafkaCluster(kafkaParams) KafkaCluster 这个类是真实负责和Kafka 交互的类,该类会获取Kafka的partition...此时会获取每个Topic的每个Partition的offset。如果配置成smallest 则拿到最早的offset,否则拿最近的offset。...这样就确定过...
Scherer C, Jeltsch F, Grimm V, Blaum N (2016) Merging trait-based and individual- based modelling: An animal functional type approach to explore the responses of birds to climatic and land use changes in semi-arid African savannas. Ecol Model 326:75-89...
a cell-type-aware transcriptome-wide association study approach that predicts cell-type-level expression, identifies disease-associated genes via combination of cell-type-level association signals for multiple cell types, and provides insight into the disease-critical cell type. As a proof of concept,...