Type 2 diabetes used to be known as maturity-onset, or non-insulin-dependent diabetes. It develops mainly in people older than the age of 40 (but can also occur in younger people). In the UK about one in 20 people aged over 65 and around one in five people aged over 85 have diabete...
www.nature.com/scientificreports OPEN Circulating long-non coding RNAs as biomarkers of left ventricular diastolic function and remodelling received: 30 June 2016 accepted: 26 October 2016 Published: 22 November 2016 in patients with well-controlled type 2 diabetes D. de Gonzalo-Calvo1,2, F....
The gp130 receptor cytokines IL-6 and CNTF improve metabolic homeostasis but have limited therapeutic use for the treatment of type 2 diabetes. Accordingly, we engineered the gp130 ligand IC7Fc, in which one gp130-binding site is removed from IL-6 and replaced with the LIF-receptor-binding ...
Type 2 diabetes differs from type 1 in that it often results from lifestyle factors and typically has a slow onset, potentially spanning years. This difference also means that it can be possible to slow the progression of the disease down even further, or perhaps even stop it, throug...
Ocular blood flow provides a new perspective for studying the effects of diabetes and ischemic heart disease on systemic blood flow, pathological mechanisms, and prognosis. Previous studies have analyzed the hemodynamic changes of the ophthalmic artery (
Type 2 diabetes (T2D) and obesity represent major challenges for global public health. They are at the forefront of international efforts to identify the genetic variation contributing to complex disease susceptibility, and recent years have seen considerable success in identifying common risk-variants....
This cohort study assesses the risk of type 2 diabetes by hemoglobin A1c (HbA1c) levels among adolescents with overweight and obesity.
Background: We investigated whether chronotype is associated with glycemic control, antidiabetic treatment, and risk of developing complications in patients with type 2 diabetes (T2DM). Methods: The diabetologists filled out an online questionnaire on th
Additionally, the integration of stem cells into OoC models may allow personalized or patient-specific therapies. Keywords: Type 1 diabetes; pancreas; organ-on-a-chip; stem cells; islets; 3D cell culture; micromachines; biosensors1. Introduction Diabetes mellitus (DM) is the most common group of...
The National Institutes of Health has several resources related to screening, diagnosis, prevention, and management of prediabetes and type 2 diabetes available at https://www.niddk.nih.gov/health-information/professionals/clinical-tools-patient-management/diabetes. The Community Preventive Services Task ...