In contrast to the IFN-λ-specific responsiveness of intestinal epithelial cells, respiratory tract epithelial cells respond to both type I and type III IFNs (Hamming et al., 2013). Accordingly, both Ifnar1−/− and Ifnlr1−/− mice are more susceptible to infection with respiratory vi...
SMA type 1 begins before 6 months of age, with generalized progressive muscle weakness and atrophy. Infants with SMA type 1 do not achieve independent sitting. Hypoventilation, poor cough strength and bulbar dysfunction lead to respiratory failure, and death usually occurs before 2 years of ...
Shah SR, Iqbal SM, Alweis R, Roark S. A closer look at heart failure in patients with concurrent diabetes mellitus using glucose lowering drugs. Expert review of clinical pharmacology. 2019 Jan:12(1):45-52. doi: 10.1080/17512433.2019.1552830. Epub 2018 Dec 3[PubMed PMID: 30488734] [15...
Low-density lipoprotein cholestenone; NICE: National Institute of Health and Care Excellence; NT-pro BNP: N-Terminal Pro-B-type Natriuretic Peptide; PDW: Platelet Distribution Width; RDW: Red Blood Cell Distribution Width; SP-D:Pulmonary SurfactantProtein-D; TAA:Thoracic aortic aneurysm;TEVAR: Tho...
Combining minor surgical procedures may be appropriate in some instances; however, extending the operation time increases the risks of respiratory complications dramatically, so caution is advised (CO). Before surgery, the patient should be assessed by a multidisciplinary team that includes a ...
研究表明,近30%的ICU患者出院之后需要长期的医疗干预来促进身体的康复,且有近1/3的患者没有能够重新返回工作岗位[4,5,6],增加了患者及其家人和照顾者的负担,具有很大的经济和社会影响。在国外PICS已经引起了医护工作者的广泛关注,并对相应的预防干预措施进行研究评价,而国内与之相关的研究报道却很少。本文对目前...
1 解热镇痛药介绍 1.1 儿童常用解热镇痛药 对乙酰氨基酚(Acetaminophen)1955年首次在美国上市,2001年在中国上市;布洛芬(Ibuprofen)1969年首次在英国上市,1999年在中国上市。二者是世界卫生组织和多国临床指南推荐用于儿童发热对症处理的治疗药物 [ 5 , 6 , 7 , 8 , 9 ]。前者为乙酰苯胺类,是非那西丁的体内代...
178 58 0 0 1 0PDF下载摘要 目的观察紫杉醇药物涂层球囊治疗冠脉支架内再狭窄的近期疗效及安全性。 方法选择辽宁省金秋医院2015年8月至2018年7月在冠脉内超声引导下实施紫杉醇药物涂层球囊治疗的冠脉支架内再狭窄患者共30例,对患者的临床资料和介入治疗结果进行分析。 结果药物涂层球囊扩张时间持续(43±11)s,药物...