Type 1 diabetes in adults: diagnosis and management. 2016. https://www.nice.org.uk/guidance/ng17. Accessed 27 Sep 2019. American Diabetes Association. Standards of Medical Care in Diabetes: 2019 abridged for primary care providers. Clin Diabetes. 2019;37(1):11–34. Article Google Scholar ...
SARS severe acute respiratory syndrome IFN interferon IFNAR type I IFN receptor IFNLR IFN-λ receptor ISGs interferon-stimulated genes PRRs pattern recognition receptors PAMPs pathogen-associated molecular patterns RIG-I retinoic acid-inducible gene 1 MDA5 melanoma differentiation-associated gene 5 LGP2 ...
In contrast to the IFN-λ-specific responsiveness of intestinal epithelial cells, respiratory tract epithelial cells respond to both type I and type III IFNs (Hamming et al., 2013). Accordingly, both Ifnar1−/− and Ifnlr1−/− mice are more susceptible to infection with respiratory vi...
Shah SR, Iqbal SM, Alweis R, Roark S. A closer look at heart failure in patients with concurrent diabetes mellitus using glucose lowering drugs. Expert review of clinical pharmacology. 2019 Jan:12(1):45-52. doi: 10.1080/17512433.2019.1552830. Epub 2018 Dec 3[PubMed PMID: 30488734] [15...
研究表明,近30%的ICU患者出院之后需要长期的医疗干预来促进身体的康复,且有近1/3的患者没有能够重新返回工作岗位[4,5,6],增加了患者及其家人和照顾者的负担,具有很大的经济和社会影响。在国外PICS已经引起了医护工作者的广泛关注,并对相应的预防干预措施进行研究评价,而国内与之相关的研究报道却很少。本文对目前...
1 解热镇痛药介绍 1.1 儿童常用解热镇痛药 对乙酰氨基酚(Acetaminophen)1955年首次在美国上市,2001年在中国上市;布洛芬(Ibuprofen)1969年首次在英国上市,1999年在中国上市。二者是世界卫生组织和多国临床指南推荐用于儿童发热对症处理的治疗药物 [ 5 , 6 , 7 , 8 , 9 ]。前者为乙酰苯胺类,是非那西丁的体内代...
Nice post and comment by Sheldon. When I was younger I went through some fairly difficult situations (e.g. divorce) and coped with depression. I wrote up my recipe for how to be happy after that [1]. I found what works for me is ...
33% of those over 50 have it and another 1 million in the UK have it undiagnosed. 1/7th of all NHS spending is related to Diabetes. It is an epidemic Health risks: Kidney failure, hearts attack, stroke, blindness, impotence, fungal and bacterial skin infections, peripheral neuralgia, foot...
NICE: National Institute of Health and Care Excellence; NT-pro BNP: N-Terminal Pro-B-type Natriuretic Peptide; PDW: Platelet Distribution Width; RDW: Red Blood Cell Distribution Width; SP-D: Pulmonary Surfactant Protein-D; TAA: Thoracic aortic aneurysm; TEVAR: Thoracic Endovascular Aortic Repair...