Modic changeBACKGROUND CONTEXT: Modic changes (MCs) are magnetic resonance imaging (MRI) evidence of inflammatory and fibrotic vertebral bone marrow lesions that associate with adjacent disc degeneration and end plate damage. Although MC etiology is uncertain, historical data suggest a linkage to an ...
Jensen TS, Karppinen J, Sorensen JS et al (2008) Vertebral endplate signal changes (Modic change): a systematic literature review of prevalence and association with non-specific low back pain. Eur Spine J 17:1407–1422. https://doi.org/10.1007/s00586-008-0770-2 Article PubMed PubMed Cen...
Presence of Modic type 1 change increases risk of postoperative pyogenic discitis following decompression surgery for lumbar canal stenosis.doi:10.1016/j.jos.2017.07.003Multicenter retrospective study.Postoperative surgical site infection is one of the most serious complications following spine surgery. ...
Four annotators identified all reports that contained Type 1 Modic change, using N=458 randomly selected lumbar spine MR reports. We then implemented a rule-based NLP algorithm in Java using regular expressions. The prevalence of Type 1 Modic change in the annotated dataset was 10%. Results ...
METHODS: Eighteen endplates showing either normal intensity signals on MRI (endplate change -), Modic Type 1 signals (low intensity on T1-weighted spin-echo images), or Modic Type 2 signals (high intensity) from patients with discogenic low back pain (n = 14) or controls requiring surgery ...
Modic changeStudy designVertebral endplate tissues were obtained from patients with degenerated lumbar disc classified as Modic type 1 or type 2 and investigated with immunohistochemical staining and the DNA nick end labelling techniques.ObjectiveTo examine the expression of fas receptor (FasR) and ...
degenerative disc diseases, resulting in a special type of discogenic back pain, in which provocative discography is typically positive and spinal MRI shows a low signal intensity on T1WI, and a high signal intensity on T2WI (Mordic-I change), indicating degenerative changes of the disc material...
Cell cycle analyses of cynaropicrin-treated AMO1 cells Afterwards, the perturbations of the cell cycle caused by cynaropicrin were explored, given that the cell cycle was one of the cellular processes that appeared to be susceptible to change (Fig. 2a). The cell cycle status of AMO1 cells...
The resveratrol treatment did not change the final data related to the obesity development (Table 1); however, the gastrocnemius mass was partially recovered (T2DMR vs. T2DM, p < 0.01). Furthermore, the body weight evolution during the 60-day resveratrol Molecules 2017, 22, 1180 3 of 13 ...
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