Diabetes means your blood glucose or blood sugar is too high. With type 1 diabetes, your pancreas does not make insulin. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose c...
Type 1 diabetes also called insulin-dependent diabetes orjuvenile diabetes, is a condition in which the beta cells of the pancreas produce little or no insulin. This results in high blood sugar levels which are not treated and can lead to other diseases like cardiovascular disease, kidney damage...
type 1 diabetes with ketoacidosis (OR = 1.07, 95% CI: 1.01-1.13, *P=1.3 x 10-2), type 1 diabetes with neurological complications (OR = 1.18, 95% CI: 1.11-1.26, ***P = 4.05 x 10-7), type 1 diabetes with ophthalmic complications (OR = 1.16, 95% CI: 1....
Ocular blood flow provides a new perspective for studying the effects of diabetes and ischemic heart disease on systemic blood flow, pathological mechanisms, and prognosis. Previous studies have analyzed the hemodynamic changes of the ophthalmic artery (OA) in patients with diabetes and ischemic heart...
their relatives.We recruited 30 type 1 diabetic subjects (10 without diabetic complications, 10 with retinopathy, and 10 with nephropathy), 36 nondiabetic siblings, 37 nondiabetic parents of type 1 diabetic subjects, and 3 control groups of healthy subjects without a family history of diabetes. ...
Type 1 diabetes (T1D) is associated with micro- and macro-vascular complications (Chang-Chen et al., 2008, Forbes and Cooper, 2013, Rask-Madsen and King, 2013, Fang et al., 2004, Schalkwijk and Stehouwer, 2005), but the mechanisms underlying their development remain elusive, due in part...
From the landmark Diabetes Control and Complications Trial in patients with T1D, it is known that longer duration of diabetes and higher HbA1c levels are associated with worse long-term diabetes outcomes, including ophthalmic complications.5 In this study, we similarly found diabetes...
1The DCCT demonstrated substantial reductions in the risk of development and progression of the early microvascular complications of diabetes over an average of 6.5 years of intensive therapy as compared with conventional therapy. At the close of the DCCT in 1993, patients in the conventional therapy...
1 Early detection and good glycemic control can prevent the progression of neuropathy in adults with T1DM.2 The International Society of Pediatric and Adolescent Diabetes recommends screening for DN from the age of 11 years in children with a diabetes duration of 2-5 years and annually thereafter...
Gaudiani, MD JAMA Key Points Question What is the association between macular vessel density as measured by optical coherence tomography angiography and visual acuity in patients with diabetic retinopathy and poorly controlled type 1 diabetes? Findings In a cohort study of 22 eyes of 22 patients ...