Type 1 Diabetes Mellitus (T1DM) is characterized by progressive autoimmune-mediated destruction of the pancreatic beta-cells leading to insulin deficiency and hyperglycemia. It is associated with significant treatment burden and necessitates life-long insulin therapy. The role of immunotherapy in the ...
Type 1 diabetes mellitus (T1DM) is characterized by beta cell loss because of an autoimmune attack. Here the authors show that an agonist for LRH-1/NR5A2, a nuclear receptor known to be protective against beta cell apoptosis, inhibits immune-mediated inflammation and hyperglycemia in T1DM mouse...
Type 1 diabetes mellitus (T1DM) is caused by autoimmune destruction of the insulin-secreting cells within the islets of Langerhans and Type 1 diabetic patients generally require exogenous insulin to survive. The autoimmune nature of this disease was elegantly demonstrated when a recipient affected by ...
Type 1 diabetes mellitus (T1DM) is a complex disease requiring constant vigilance and special training to ensure healthy outcomes. A collaborative relationship between the child with T1DM and his or her parents is essential for proper monitoring and care. Adolescence rep...
PURPOSE: This study analyzed the expression of HLA-DR and DQ genotypes and anti-thyroid autoantibodies[anti-thyroid peroxidase (TPO) and anti-thyroglobulin (TG) antibodies] in Korean patients with type 1 diabetes (T1DM) to investigate the susceptible HLA alleles to T1DM in Korea and the prevalenc...
Type 1 diabetes (T1DM) is increasing in incidence worldwide, particularly in young children. Studies have suggested that weight gain in early childhood may play a role in determining disease risk, with increased risk in children who have gained more weight. We hypothesized that leptin may be inv...
1)Childhood type 1 diabetes mellitus儿童1型糖尿病(T1DM) 2)Children type 1 diabetic mellitus儿童1型糖尿病 英文短句/例句 1.Objective To investigate the incidence rate( IR) of IDDM in the children of Nanning.目的调查南宁市儿童1型糖尿病的发病率。 2.Study on the Incidence Rate of Childhood Type...
Various data on type 1 diabetes mellitus (T1DM) have showed that the incidence of T1DM peaks at puberty. However, diabetes control and complications could be adversely affected by the physiological changes of puberty. In early years of insulin therapy, severe growth retardation with pubertal delay,...
Type 1 diabetes mellitus (T1DM) is a chronic, progressive autoimmune disease characterized by metabolic decompensation often leading to dehydration and ketoacidosis. Viral agents seem to play an important role in triggering the autoimmune destruction that leads to the development of T1DM. Among several ...
Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic β-cell loss and leads to hyperglycaemia. Although the age of symptomatic onset is usually during childhood or adolescence, symptoms can sometimes develop muc...