Despite major advances over the past decade, prevention and treatment of type 1 diabetes mellitus (T1DM) remain suboptimal, with large and unexplained variations in individual responses to interventions. The cu
This article reviews our current understanding of the etiology, presentation, and management of type 1 diabetes. The discussion includes a review of the natural history of diabetes, the complex relationship between genetic and environmental risk for type 1 diabetes, and current methods for prediction ...
Interleukin 1 (IL-1) has important functions in innate and adaptive immunity. Blocking IL-1 action has clinical efficacy in many inflammatory diseases, including type 2 diabetes mellitus. Here, the authors review the mechanisms of IL-1 action that lead t
Immune therapy for type 1 diabetes mellitus can be approached at three different stages: primary prevention, secondary prevention and intervention. This Review discusses the different types of immune therapies being attempted at these three different sta
Type 2 Diabetes: Signs, Symptoms, Treatments See Slideshow What are the different types of diabetes? There are two major types of diabetes, called type 1 and type 2. In type 1 diabetes, formerly called insulin-dependent diabetes mellitus (IDDM), or juvenile-onset diabetes mellitus, the pancr...
Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic β-cell loss and leads to hyperglycaemia. Although the age of symptomatic onset is usually during childhood or adolescence, symptoms can sometimes develop muc...
This systematic review and meta-analysis aimed to synthesize evidence on the association between Type 1 diabetes mellitus (Type 1 diabetes) and dementia risk. A systematic search of CINAHL, EMBASE, MEDLINE, PSYCINFO, and Web of Science databases identified 19 relevant studies for inclusion. Studies...
1:51-55 DIABETES MELLITUS TYPE 1 THE PRESENT AND THE FUTURE JOSÉ BARBOSA, PERE SANTAMARIA Division of Endocnnology and Metabolism. University of Minnesota, Minneapolis, Minnesota. U.S.A. RESUMO Diabetes Mellitus tipo 1: o Presente e o Futuro A Diabetes Mellitus Insulino Dependente (DID) ...
Type 2 diabeteswas also previously referred to as non-insulin-dependent diabetesmellitus (NIDDM), or adult-onset diabetes mellitus (AODM). In type 2 diabetes, patients can still produce insulin but do so relatively inadequately for their body's needs, particularly in the face ofinsulin resistance...
Clinicians and patients with type 1 diabetes mellitus eagerly await the successful use of stem cell-derived β cells in clinical practice. This Review provides a summary of current strategies to obtain cells which express insulin from different progenito