According to the first point of view about the physiopathology and management of type 1diabetes, it seems to be easy but as we go deep into its study the less it seems to be known. Koch's postulates are not followed in all the cases of type 1 diabetes mellitus, and this is concluded...
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Type 1 diabetes is characterized by β-cell destruction leading to absolute insulin deficiency [1]. The most common cause of β-cell destruction is immune-mediated (type 1A) while in rare cases no immune markers can be found (type 1B, etiology unknown). When untreated, the patients experienc...
DIABETES MELLITUS (DM) comprises e heterogeneous group of hypoglycemic disorders, that are grouped according to their physiopathology and etiology; the most notorious ones are type 1 DM (DM1) and type 2 DM (DM2); DM1 is characterized by early onset and absolute lack of insulin; therefore, ...
Type 1 Diabetes Mellitus英文电子书.pdf,Type 1 Diabetes Mellitus (See also Harrison’s Principles of Internal Medicine, 17th Edition, Chapter 338) Definition • Diabetes mellitus (DM) comprises a group of common metabolic disorders that share the phenot
Type 1 diabetes is an autoimmune disorder that causes pancreatic β-cell destruction. This destruction leads to insulin deficiency that results in hyperglycemia and disrupts energy storage and metabolism. Severe insulin deficiency can lead to ketosis, acidosis, dehydration, shock, and death. Epidemiolog...
The incidence of type 1 diabetes has been increasing worldwide. Its etiology is complex and remains unknown. In this review, possible genetic factors associated with the susceptibility of type 1 diabetes are discussed.doi:10.5472/mmj.2011.01874.0Eroglu Altinova, Alev...
Diabetes Type 1 (Insulin-Dependent Diabetes Mellitus) Lisa K. Gilliam, Åke Lernmark Choose an option to locate/access this article: Check if you have access through your login credentials or your institutionCheck access Purchase $31.50 Show more Show less http://dx.doi.org/10.1016/B0-...
Diabetes meliitus is defined by the WHO (1) as a state of chronic hyperglycaemia. The main hypoglycaemic factor, insulin, is a hormone produced by the B-cells of the islets of Langerhans in the pancreas. An increase in the blood glucose level leads to in
Despite major advances over the past decade, prevention and treatment of type 1 diabetes mellitus (T1DM) remain suboptimal, with large and unexplained variations in individual responses to interventions. The current classification schema for diabetes mellitus does not capture the complexity of this diseas...