the syndrome of positive symptoms which responds to drugs is a neurochemical disturbance and associated with an increase in numbers of D2 dopamine receptors; the other, a syndrome of negative symptoms and intellectual impairment, may be a consequence of a degenerative process leading to cell loss....
progressive disorder involving multiple stages and processes [4,5], it is a remarkable fact that none of these studies have demonstrated a within-child correlation between any prenatal stage or process and the severity of an ASD child’s social symptoms. Moreover, studies have not identified pren...
It remains unknown in our patient whether the psychosis should be attributed to schizophrenia or SCA2, but this case highlights the need for awareness of neurodegenerative disorders in patients with psychiatric symptoms, in particular in patients who are treated with neuroleptics and exhibit ...
SchizophreniaSeveral lines evidence indicate that the non-competitiveN-methyl-d-aspartate (NMDA) receptor antagonist ketamine and the mixed dopamine (DA) D1/D2receptor agonist apomorphine induce schizophrenia-like symptoms in rodents, including memory impairments and social withdrawal. Nitric oxide (NO)...
Objective: The hypothesis that cognitive decline and psychiatric symptoms are independent disease processes was tested. Methods: The relationship between cognitive functioning and clinical symptoms was examined in a large sample of 100 schizophrenia patients. Results: The hypothesis was largely confirmed. ...
A total of 609 subjects were recruited for this study, including 276 DDH patients and 318 healthy individuals. All patients with DDH were diagnosed by orthopedic experts according to their medical history, clinical symptoms and imaging results (hip X-ray, magnetic resonance imaging and ultrasound),...
While currently available drugs are effective in managing psychotic episodes in most patients, they have a modest effect on negative and cognitive symptoms of schizophrenia, both of which are commonly present throughout the disease course and substantially impact functioning. Antipsychotics are also ...
Methods: 10 adults with schizophrenia (mean age 31,5 years) and 6 psychotic adolescents with schizophrenic symptoms (mean age 16,2 years) underwent functional magnetic resonance imaging while performing two frontal tasks. Regional activation is compared in the bilateral frontal areas during a covert ...
Certain explanations of these inconsistencies have related them to different syndromes of schizophrenia (Green et al., 1983) and to different factors of schizotypy (Broks et al., 1984; Gruzelier and Doig, 1996). Recent popular classifications of symptoms of schizophrenia usually consist of from t...
This article reflects on symptoms of paranoid schizophrenia (voice hearing) and speculates that these could be caused by either telepathy or trauma. It discusses supporting literature, arguments and evidence for both assumptions. The article then integrates these two perspectives into one synthetic ...