O2consumption during incubations was recorded using a closed O2electrode and H2O2was quantified via oxygen release after catalase addition. As shown in Fig.2a, all metabolites, compared to methanol control, elicited H2O2production, whereas negligible amount...
Based on these results, cyanohydrin ester formation using acids (1R*,2S*)-6 and (1R*,2R*)-6 was carried out. Conventional condensation reactions of (1R*,2S*)-6 and (1R*,2R*)-6 with bromo(3-phenoxyphenyl)acetonitrile [9] produced target cyanohydrin esters (1R*,2S*)-8 and (1R*,...