FOXO3 is consistently annotated as a human longevity gene. However, functional variants and underlying mechanisms for the association remain unknown. Here, we perform resequencing of the FOXO3 locus and single-nucleotide variant (SNV) genotyping in three
Explain the basic structure of proteins. Give at least two major functions. Proteins: Proteins can be referred to as the most versatile biological polymers found in the human body. They are essential nutrient for human body and act as fuel source. ...
We find that these diverse parasitic strategies both originated from lateral gene transfer, followed with duplication and specialization, and that they might contribute to the shift in host ranges between parasitoids. Our results increase our understanding of how novel gene functions originate and how ...
Computational Design of a PAK1 Binding Protein We describe a computational protocol, called DDMI, for redesigning scaffold proteins to bind to a specified region on a target protein. The DDMI protocol i... RK Jha,A Leaver-Fay,S Yin,... - 《Journal of Molecular Biology》 被引量: 122发表...
The usual two-body score (energy) function to recognize native folds of proteins is Miyazawa鈥揓ernigan (MJ) pairwise-contact function. The pairwise-contact parameters between two amino acids in MJ function are symmetric in a sense that a directional order of amino acids sequence along the ...
Although insects possess storage hexamerins, very little is known about the character and specific functions of hexamerin 1 and storage protein 1 in insect development. Results To gain insight into the function of storage proteins in insects, cDNAs for two storage proteins were cloned from the ...
(1)推理判断题。根据第一段A protein is a large,complex macromolecule composed of one or more long chains of amino acids (氨基酸).Present in and vital to every living cell,proteins are essential for the structure,function,and regulation of the body
It was concluded that the efficiency of amino acid utilization may depend on genotype, perhaps due to differences in the relative proportion of different protein fractions to whole body protein and due to differences in the ratio of synthesis and degradation of body proteins. Nonlinear relationships ...
This poorer immunomodulation function in comparison with the ion exchange procedure is ascribed to the modifications occurring in the Fc portion of immunoglobulin during the alkylation and acylation of proteins in β-propiolactonation37,38. It is noteworthy that TBSF undergoes purification through anion...
This database integrates biological data and analytical methods, thereby enabling the systematic annotation of biological functions for extensive lists of genes or proteins. Results were considered statistically significant for P < 0.05 and potentially statistically significant for 0.05 < P <...