We present two rare and fatal forms of anthrax: meningeal in a 33-year-old male shepherd and intestinal in a 4-year-old boy. The former was admitted to the hospital with complaints of headache, vomiting, fever, and decreased level of consciousness. The latter presented with abdominal pain ...
SMITH, and Stanley (1955) demonstrated that Bacillus anthracis growing in vivo forms a specific oedema-producing toxin which is responsible for death of the host. This toxin, present in the plasma of guinea-pigs dying of anthrax, has not been produced by culture in vitro. It is unrelated to...
T Cell Targeting by Anthrax Toxins: Two Faces of the Same Coin Bacillus anthracis, similar to other bacterial pathogens, has evolved effective immune evasion strategies to prolong its survival in the host, thus ensurin... SR Paccani,CT Baldari - 《Toxins》 被引量: 23发表: 2011年 Two faces...
Pore-forming toxins (PFT) are virulence factors that transform from soluble to membrane-bound states. The Yersinia YaxAB system represents a family of binary α-PFTs with orthologues in human, insect, and plant pathogens, with unknown structures. YaxAB w
The Ebola virus would spread more rapidly if it became airborne and less virulent, as would anthrax bacteria that were trans- missible from an infected human host to an uninfected human. The fact that these features have not emerged in these infectious agents indicates the difficulty that ...
Grease, anthraxgate, and kennel cough: A revisionist history of early veterinary vaccines In conclusion, it is remarkable just how farsighted many of the early vaccine investigators were. Jenner was apparently very comfortable with contagion and......
In contrast to collagen binding to VLA-2, echovirus 1 interactions do not discriminate between functional forms of the receptor, and are not enhanced by activating antibodies or phorbol esters (9). In addition, whereas VLA-2 interaction with collagen is magnesium-dependent, echovirus 1 attachment...
Some of them were a little heavier than I like (Dio, Ozzy, Korn, Anthrax — the Obituary song (Dying) was very cool musically, but the vocalist was a little too death metal for my tastes), but in general, they were all similar. I just added Rush to the station, so it should ...
Strand β4 then forms part of a β-hairpin with β3 before being followed by an extended loop that winds around and extends over the top of β-sheet 1. This is followed by strand β5 that forms a β-hairpin with strand β6 and together with strands β1 and β2 comprise β-sheet ...
Cellular RNA polymerases (RNAPs) are viewed as well-tuned engines that promptly re-initiate a new round of transcription after termination. For example, bacterial RNAPs minimally comprise an α2ββ’ω subunit catalytic core, which forms a holoenzyme with one of several σ factors to initiate ...