links to metastasis and tumor immune regulation.30However, despite these advancements, our understanding of CIN remains incomplete. The complex nature of CIN, its causes and consequences, as well as the paradox of CIN, necessitate a systematic review. This is particularly important, given the potent...
It is well accepted that GSEA has multiple advantages over analyses performed on the level of individual genes46,47,48. GSEA evaluates gene expression on the level of gene sets that are based on prior biological knowledge, GSEA is unbiased, because no gene selection step (fold change and/or ...
And fructose and mannose metabolism were found to be closely related to glycolysis and may provide substrates for sugar nucleotide synthesis in the previous studies [39], which may interact with the energy metabolism in muscle. This study has several advantages. At first, a wide range of blood ...
Loss of FBP1 by snail-mediated repression provides metabolic advantages in basal-like breast cancer Cancer Cell (2013) D. Hanahan et al. Hallmarks of cancer: the next generation Cell (2011)View more references Cited by (127) Cancer cells co-opt nociceptive nerves to thrive in nutrient-poor ...
In the last decades, polymer materials are widely used to package food because of their advantages including easy shape formation, durability, lightweight, recyclability, and transformability. During the manufacturing process of polymer materials, additives such as antioxidants, light stabilizers, plasticize...
Aging is neither a direct product of evolution via natural selection (such as a program determining lifespan) nor a byproduct (delayed payment for current advantages). Aging results from the limitations imposed by the immanent physicochemical properties of metabolites on the capabilities and outcomes ...
Despite these advantages, when grown together, MCF-7 cells do not always outcompete MDA-MB-231 cells. MDA-MB-231 cells outcompete MCF-7 cells in low glucose conditions and coexistence is achieved in low pH conditions. Under all conditions, MDA-MB-231 has a stronger competitive effect (...
Recently, several studies have shown that lactic-acid-producing thermophiles might have substantial advantages over the traditionally used mesophilic strains, such as Lactococcus lactis and Lactobacillus rhamnosus. Not only do these organisms have general advantages in terms of fermentation at high ...
Genetic forecasting of shifts in the abundance of particular gut microbiota taxa linked to BCa is essential and achievable for constructing risk evaluation models. Modulation of the microbiota could offer potential advantages for urinary tract health [29]. Our study highlights various gut microbiota ...
The advantages of this approach are demonstrated in greater detail below. The examples described in greater detail below show the efficacy of the coupled two-way clustering algorithm of the present invention, as implemented with the super-paramagnetic clustering algorithm (SPC), which is known in ...