025 Tumor-stromal cell interactions modulate metalloproteinase and kalli Krein expression in direct and indirect co-culture cell models. Revue des Maladies Respiratoires. 2008; 25 :1167. (translated)Brillet, B.; Petiot, S.; Iochmann, S.; Gaud.; Planque, C.; Blechet, C.; Heuze-Vourc'h...
Thomas and Radhakrishnan Molecular Cancer https://doi.org/10.1186/s12943-018-0927-5 (2019) 18:14 REVIEW Tumor-stromal crosstalk in pancreatic cancer and tissue fibrosis Divya Thomas1 and Prakash Radhakrishnan1,2,3,4* Open Access Abstract Pancreatic ductal adenocarcinoma (PDAC) is a devastating ...
Thus, similar to tumor cells, the heterogeneity of tumor-stromal fibroblasts probably influences the outcome of patients with IDC of the breast. 展开 关键词: INVASIVE DUCTAL CARCINOMA CANCER-ASSOCIATED FIBROBLASTS HISTOPATHOLOGICAL PROGNOSTIC PARAMETER CENTRAL ACELLULAR ZONES EARLY DISTANT RELAPSE FIBROTIC ...
In 1983 the term stromal tumor was first used to describe a series of gastric tumors that appeared to arise not from smooth muscle but rather from nerve sheath cells that did not resemble typical Schwann cells.2 This initial distinction was based on IHC and electron microscopic analysis that de...
The contribution of stromal cells to the microenvironment of tumor-draining lymph nodes is poorly characterized. By comparative transcriptional analysis, Shields and colleagues find that tumors induce the stromal reprogramming of key pathways that affect
4、印戒细胞样间质瘤(signet-ring stromal tumour) ① 肿瘤具有纤维瘤样背景 ② 可见不同数量印戒样细胞(单个胞浆空泡、核偏位),但细胞内缺乏黏液、糖原和脂质 ③ 可见嗜酸性透明小球 ④ 核异型性小,可见核仁,偶见核沟 ⑤ 核分裂象少见 ⑥ 缺乏:假小叶、鹿角型血管 ...
Tumor-stromal cross talk: direct cell-to-cell transfer of oncogenic microRNAs via tunneling nanotubes Tunneling nanotubes (TnTs) represent a novel mechanism by which intercellular components such as proteins, Golgi vesicles, and mitochondria can be transfer......
Introduction: Chronic inflammatory responses within the colonic environment are critical to colorectal cancer (CRC) tumor development. While the exact causes of CRC development are unknown, recent data suggest that dysbiosis in the colon... G Uribe,R Rourke,R Villeger,... - 《Cancer Research》 ...
CONTROL OF LOW-RESOLUTION SCANNING OF OVARIAN TUMOR STROMAL COMPARTMENT. NICOLAS ELIE,ALEXANDRE LABICHE,JEAN-JACQUES MICHELS,PAULETTE HERLIN. Image Analysis and Stereology . 2005Elie N, Labiche A, Michels J-J, Herlin P. Control of low-resolution scanning of ovarian tumor stromal compartment. Image...
Here, we report that C- X -C motif chemokine receptor 4 (CXCR4) and hedgehog pathways cooperate in PC chemoresistance via bidirectional tumor-stromal crosstalk. We show that when PC cells are co-cultured with pancreatic stellate cells (PSCs) they are significantly more resistant to gemcitabine ...