We recently reported that tumor stroma-derived angiopoietin-like protein 2 (ANGPTL2) has tumor suppressive activity by enhancing dendritic cell-mediated CD8+ T cell anti-tumor immune responses. However, a direct
www.nature.com/scientificreports OPEN Simulating the human colorectal cancer microenvironment in 3D tumor-stroma co-cultures in vitro and in vivo Mahesh Devarasetty1, Anthony Dominijanni1, Samuel Herberg2, Ethan Shelkey1, Aleksander Skardal3 & Shay Soker1 ✉ The tumor ...
Thus, although new models are being developed, the complexity of the tumor stroma in vitro has not yet been achieved. Nevertheless, recent advances in 3D cancer models have the potential to (i) improve drug discovery, (ii) be used as platforms for drug testing, and (iii) enable the ...
Quantitative and Qualitative Metrics of Tumor-Stroma in Predicting Ovarian Cancer Outcomes and Expansion of its Study with AI-Based Tools Epithelial ovarian cancer remains one of the deadliest gynecologic malignancies, with late-stage diagnosis, high recurrence rates, and resistance to platinum-based ...
1)tumor stroma肿瘤间质 1.Myofibroblasts,which are key cells of tumor stroma,play an important role in the tumor angiogenesis.间质肌纤维母细胞通过旁分泌或自分泌的形式参与肿瘤间质重构和促血管形成因子的产生,直接或间接促使内皮细胞和血管周细胞的分化、增殖以及募集,促进肿瘤性血管形成。 2.As the predo...
网络释义 1. 肿瘤基质 近些年来,研究者们发现,肿瘤细胞的发展壮大,恶性迁移,都和它周围的邻居——肿瘤基质(Tumor Stroma)有着密不可分 … www.guokr.com|基于3个网页 例句
Fusenig NE, Skobe M, Vosseler S, Hansen M, Lederle W, Airola K et al (2002) Tissue models to study tumor-stroma interactions. In: Foidart JM, Muschel RJ (eds) Proteases and their inhibitors in cancer metastasis. Cancer metastasis — biology and treatment, vol 4. Springer, Dordrecht ...
tumor-stroma 青云英语翻译 请在下面的文本框内输入文字,然后点击开始翻译按钮进行翻译,如果您看不到结果,请重新翻译! 翻译结果1翻译结果2翻译结果3翻译结果4翻译结果5 翻译结果1复制译文编辑译文朗读译文返回顶部 正在翻译,请等待... 翻译结果2复制译文编辑译文朗读译文返回顶部...
胰腺导管腺癌(PDAC)富含与癌症相关的成纤维细胞(CAFs),这些细胞参与了肿瘤间质的形成。然而,PDAC致密的肿瘤间质是药物传递的主要障碍,从而阻碍了PDAC的治疗。考虑到PDAC特殊的肿瘤微环境,我们构建了一种新型的纳米颗粒,该颗粒对膜生物标志物FAP-α在CAFs和近红外(NIR)激光照射下反应。将具有较强肿瘤穿透能力的紫杉醇...
On in vivo examination, CAFs promoted tumor progression, and PFD suppressed tumor progression with an inhibitory effect on tumor-stroma crosstalk. PFD might inhibit not only fibroblast activity, but also the crosstalk between cancer cells and fibroblasts. PFD may have great potential as a novel ...