calculation formula of tumor volume was: volume = (tumor length × tumor width2)/2. When the mice died, the survival time was recorded. After the mice died, the tumor were collected for H&E staining, TUNEL assay and Ki67 staining. ...
In the B16 xenograft model, we found that anlotinib reduced the mortality in mice and decreased the volume and weight of tumors (Fig.5a–d). In the MC38 group, anlotinib also decreased the size of the transplanted tumors (Fig.S2b). However, treatment with bevacizumab increased the mortality,...
700 mm3, based on the calculation of the difference between logarithmic tumor volume from the different formulas versus logarithmic volume of extirpated and dissected tumors and regression analyses, volume of the unremoved liver tumor can be best calculated according to the formula V = a x b2/2....
Calculation of tumor burden Rip1-Tag2 mice in each treatment were sacrificed at the defined end points. Solid tumors were isolated, photographed, and measured. The tumor volume was calculated using the following formula: volume = 0.52 × (width)2× (length). Tumor burden per mouse was defined...
and repeat regions, driver mutations and germline mutations were removed via using population online databases (The Exome Aggregation Consortium v.03, Genome Aggregation Database, and 1000 Genome) followed by variant allelic frequency cutoff of 0.2%. The tumor mutation calculation formula was as ...
Different from caliper measurements, tumor volume calculation is done by the software, based upon the tumor area, or region of interest, automatically detected and set by the algorithm. No assumed tumor model and constant shape are set by using a tumor volume formula. When a balance scale is ...
Tumor volume calculation The two axes CT scan measurements and the equation for the ellipsoid volume were used to estimate tumor volumes:V=43π×a×b×c Where a and b are the two axes and c is their mean. Mutation calling Reads with mapping quality below 30 in the BAM files were filtere...
(b) were measured and recorded at each injection. The calculation formula of tumor volume (V) was: V=(a×b2)/2. The tumor volume exceeding 1,000 mm3or the weight loss exceeding 15% was taken as an endpoint of the experiment. The mice were euthanized, and the experiment was terminated...
Tumors were measured at indicated times and tumor volume was calculated using the formula: π/6 × length × width2. GEO and TARGET data analysis The results of this study were partly generated by analysis of data from TARGET and GEO datasets: GSE21257, GSE30699, GSE33382, and ...
(Corning) and normal DMEM medium. Tumor size was measured in a blinded fashion three times weekly with a caliper and tumor volume was calculated using the following formula: ½ × length (mm) × width (mm)2. Randomization occurred in a blinded fashion, when tumors reached an ...