Cells showing the exogenous expression of Gros1-L show a significantly decreased colony formation ratio, while cells showing the expression of Gros1 antisense RNA show a significantly increased colony formation ratio.ワダワ レヌー杉原 崇吉田 暁子...
2.1.3Tumor suppressor genes Atumor suppressor geneis a gene that protects cellsfrom uncontrolled growth. When this gene is mutated (having a loss or reduction in its function), a cell can progress to cancer, usually in combination with othergeneticchanges. Tumor-suppressor genes, or the proteins...
肿瘤抑制基因(tumor suppressor gene) 相关知识点: 试题来源: 解析 答案: 肿瘤抑制基因又称隐性癌基因或抗癌基因,是指一类存在于正常细胞中的、与原癌基因共同调控细胞生长和分化的基因。当一对抗癌基因均丢失或突变时,即该基因隐性纯合时,细胞会发生癌变。 解析:空 3、填空题(45分,每题5分) 1. 染色体畸变在...
tumor suppressor gene noun variants or tumor-suppressor gene : any of a class of genes (as p53 and APC) that act in normal cells to inhibit unrestrained cell division and that when inactivated (as by mutation) place the cell at increased risk for malignant proliferation In some cases [...
1. Tumor suppressor gene malfunctioning is caused by mutations in both alleles or a mutation in one followed by a loss of or reduction to homozygosity in the second. 【隐性失活】 2. Mutation may occur in germ cell (can be inherited) or somatic cells. 【可遗传,比如APC导致的FAP】 ...
抑癌基因 （tumor suppressor gene)概述：抑癌基因：在正常情况下，细胞内的一类基因产物能抑制细胞生长并能潜在抑制细胞癌变，当通过纯合缺失或失活可引起恶性转化的基因群,又称为隐性癌基因、抗癌基因或肿瘤易感基因。抑癌基因的作用：在调控细胞生长、增殖及分化过程中起负调控作用，并能潜在地抑制肿瘤的生长。如果...
15.2抑癌基因 Tumor suppressor gene(上) 1298 播放芭比衣橱 收藏 下载 分享 手机看 登录后可发评论 评论沙发是我的～选集(126) 自动播放 [1] 1绪论 2316播放 03:52 [2] 2.1氨基酸的结构Structur... 970播放 05:42 [3] 2.2氨基酸的分类与性质Class... 651播放 06:56 [4] 2.2氨基酸的...
肿瘤抑制基因(tumor suppressor gene) 正确答案 ①固有基因;②与原癌基因编码的蛋白质促进细胞生长功能相反;③该基因突变失活或其功能丧失,可能促进细胞的肿瘤性转化。 答案解析 略 真诚赞赏,手留余香 小额打赏 169人已赞赏
[名词解释] Tumor suppressor gene (抑癌基因) 相关知识点: 试题来源: 解析 又称肿瘤抑制基因,是细胞的制动器(brake),它们编码的蛋白质抑制细胞生长,并阻止细胞癌变。在正常的二倍体细胞中,每一种抑癌基因都有两个拷贝,只有当两个拷贝都丢失了或两个拷贝都失活了才会使细胞失去增殖的控制,只要有一个拷贝是...
TUMOR SUPPRESSOR GENE 专利名称：TUMOR SUPPRESSOR GENE 发明人：GELMAN, Irwin,JAKEN, Susan 申请号：US1997006830 申请日：19970418 公开号：WO97/040059P1 公开日：19971030 专利内容由知识产权出版社提供 摘要：The present invention relates to a novel tumor suppressor gene, SSeCKS. The SSeCKS gene product...