Docetaxel and Fulvestrant treatment reduced spheroid sizes of alginate-BR and embedded samples, confirm- ing the results from fluorescence-based growth curves (Fig. 4B). Analysis of tumor spheroid size and numbers in situ represents a relatively simple imaging tool that may be used to validate ...
D-E Cellular distribution of GPR65 in glioma using single-cell RNA-seq datasets from UCSC Cell Browser (https://gbm.cells.ucsc.edu) and Single Cell Portal (https://singlecell.broadinstitute.org, GSE131928). F Representative pictures and quantification for immunofluorescence staining of clinical ...
Future improvements will improve ease and allow the network to detect tumors of all sorts and sizes. Using this method, we hope to contribute new ideas and focus on classifying different cancers. The method may also be more broadly applicable to a wider variety of clinical situations if ...
The percentage of CD45, CD68, CD8, Ki67, and Cleaved Caspase 3 positive cells were quantified using a customized cellular multiplex algorithm. Scripts were produced for the analysis methodology of all the above slide pictures. These scripts were then executed in batches for each set of images ...
As shown in Figure 6, mice vaccinated against VEGFR-2 and mated one week later failed to become pregnant, whereas if mating was delayed for 8 weeks the VEGFR-2–immunized mice were fertile, with litter sizes and average weights of offspring comparable with nonimmunized mice. These observations...
Future improvements will improve ease and allow the network to detect tumors of all sorts and sizes. Using this method, we hope to contribute new ideas and focus on classifying different cancers. The method may also be more broadly applicable to a wider variety of clinical situations if ...
Finally, laser scanning confocal microscopy was used to determine the cells' viability with and without formalin fixation. In vivo antitumor effect Mice bearing HeLa tumors in the right flank, with average tumor sizes of 500 mm3, were used to assess the in vivo antineoplastic efficiency. The ...
(MDA-MB468) were treated twice weekly with M69-DOX at either 20 or 10 mg/kg, as well as treated with DOX at 2 mg/kg. While the tumor sizes of the mice in the untreated control group were markedly increased at the third week, tumor growth in the mice treated with M69-DOX at ...
pictures from colon tumors.n ≥ 4 images for each condition. Bars, 100 μm. Data represent mean ± SEM (n = 4 tumors).bImmunostaining analysis of colon tumors induced by AOM/DSS in WT or p38αΔUbmice. The percentages of CD31+, CD105+, CD34+, and PDGFRB+cells ...
Exosomes are small membrane-bound vesicles with sizes ranging from 30 to 100 nm3 that contain informational molecules such as proteins, mRNA, and lipids. Therefore, exosomes are well known by the “exosomal shuttle” that delivers oncogenic microRNAs (miRNAs), mRNAs, noncoding RNAs, and proteins...