Knowing that bile acids can control the expression of CXCL16, the investigators treated mice with bile acids, so they changed the number of NKT cells in the liver, and thereby the number of tumors in the liver. Bile acids are formed in the liver and help break down fats during digestion....
Editorial: 3D Segmentation in the Clinic: A Grand Challenge II -Liver Tumor Segmentation In this paper, we present the organization of a competition of liver tumor segmentation techniques. The liver tumor segmentation competition is part of the workshop "3D Segmentation in the Clinic: A Grand ...
Primary hepatic neuroendocrine carcinoma in a child: morphological, immunocytological, and molecular biologic studies. Cancer 1993;71:2600–2605. Article Google Scholar Imaoka I, Sugimura K, Tamura K. Case report: MR imaging of a carcinoid tumor of the liver. Clin Radiol 1993;47:287–289. ...
Segmentation of the liver and liver tumors is a useful and sometimes necessary pre-processing step in the planning of many liver cancer therapies, such as radiofrequency ablation or selective internal radiation therapy (SIRT), but is also very time-consuming when performed manually. In recent years...
As phosphatase and tensin homolog (PTEN) loss is the most common genetic lesion in such cancer, we investigate human data sets for mechanisms that can constrain cancer evolution in this setting. Here we report a liver X receptor (LXR) signature, which tightly correlates with PTEN loss, in ...
Benign and malignant solid tumors of many types are observed in mice of both sexes, the most frequent being in the lung, liver and ovary. However, evidence for a radiation response is limited to the case of Harderian gland neoplasms. In addition, a comparison of the observed frequency of ...
The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities Introduction Breast cancer is the most diagnosed malignancy in females, with about 2.3 million new cases globally in the year 2020, which accounted for 11.7% of al...
Remarkably high reduction of tumorigenesis and induction of apoptosis in the liver section was obtained in mouse models of hepatocellular carcinoma after oral administration of barely shochu distillation remnants in vivo [19]. Our previous research showed that fermented barley extract could significantly ...
In order to assess the effect of CD47 on in vivo tumor metastasis, A549 transfected with control shRNA or CD47-shRNA was injected through the tail vein and quantified the number of metastatic foci in the liver after four weeks23. As shown in Fig. 5D, mice injected with CD47-shRNA cells...
The polyploid state plays a tumor-suppressive role in the liver. Dev. Cell. 47(3), 390. https://doi.org/10.1016/j.devcel.2018.10.020 (2018). Article CAS PubMed PubMed Central Google Scholar Debies, M. T. et al. Tumor escape in a Wnt1-dependent mouse breast cancer model is ena...