The tumor cells are positive for synaptophysin, chromogranin, CDX2, and ER (weak); and negative for CK7 and GATA3. These immunophenotypic features, in conjunction with the clinical history and cellular morphology, support the diagnosis of metastatic well-differentiated neuroendocrine tumor with ileal...
The tumor cells were positive for S-100 protein, SOX10, and vimentin in 100% of cases, for CD56 in 70%, for synaptophysin in 56%, for NB84 in 50%, for NSE in 45%, and for neurofilament protein in 14% of cases. All cases tested were negative for specific melanocytic, ...
3C). Immunohistochemically, the tumor cells were positive for synaptophysin (Fig. 3D), chromogranin, and CD56. The Ki-67 labeling index was 4.4% in the hotspot (Fig. 3E). Download: Download high-res image (776KB) Download: Download full-size image Fig. 1. Treatment of a rectal ...
Histopathologically, the tumor cells were positive for chromogranin A, synaptophysin and CD56. Scattered sustentacular cells were positive for S-100 protein. Moreover the specimens showed vessel invasion and extracapsular tumor invasion. This case was diagnosed as malignant CBT taking both the clinical...
Microscopically, the tumor consisted predominantly of a diffuse proliferation of small oat cells. The tumor cells were positive for neuroendocrine markers chromogranin A and synaptophysin. One of 16 lymph nodes was metastatic. A correct treatment needs to be chosen. Conclusions It has recently been ...
a small, yellow tumor that may develop from argentaffin cells in the gastrointestinal mucosa and spread widely throughout the body. See also:Cancer -Ologies & -Isms. Copyright 2008 The Gale Group, Inc. All rights reserved. ThesaurusAntonymsRelated WordsSynonymsLegend: ...
T cells with positive Ki-67 nuclear expression were proliferating, and PD-1 positivity denoted PD-1+ T cells. Expression of synaptophysin identified tumor cells. (B) Quantification of CD4+ T cell, CD8+ T cell, and Treg cell density (cells per mm2), as well as proliferating and PD-1+ ...
Histopathological examination of the tumor biopsy specimen showed that the tumor was composed of uniform round-to-oval cells with solid arrangement and the tumor cells stained positive for chromogranin A, synaptophysin, and neuron-specific enolase. We diagnosed this case as an intrahepatic metastasis ...
Carcinoid tumor, as the glomus tumor, can show an organoid pattern, increased vascularity, and uniform, round cells with eosinophilic cytoplasm, but usually are positive for cytokeratin and always stained with chromogranin and synaptophysin, showing negative for smooth muscle markers as presented in our...
The targeted neoplastic cells were strongly positive for Synaptophysin, CD56, Chromogranin, while negative for other markers. Thus, the immunostaining results from the cervical lymph node and bone marrow biopsy is consistent with poorly differentiated metastatic neuroblastoma (Fig. 3A-D). Download: ...