The tumor epithelial cells were positive for pan-cytokeratins (AE1 and AE3). Langerhans cells demonstrated by anti-CD1a staining were found in nests or strands of tumor epithelial cells. The eosinophilic globule
Circulating Tumor Cells (CTCs) in blood encompass DNA, RNA, and protein biomarkers, but clinical utility is limited by their rarity. To enable tumor epitope-agnostic interrogation of large blood volumes, we developed a high-throughput microfluidic device, depleting hematopoietic cells through high-flow...
Desmoplastic small round cell tumor is a tumor composed of small round cells associated with marked desmoplasia and multiphenotypic differentiation. From: Comprehensive Cytopathology (Third Edition), 2008 About this pageSet alert Also in subject areas: Nursing and Health Professions Pharmacology, Toxicology...
Cells staining positive for pan-CK and Hoechst (nuclei stain) and negative for CD45 with characteristic morphology of cancer cells (i.e., high nucleus to cytoplasm ratio) are identified as CTCs. Cells staining positively for CD45 and Hoechst and negatively for pan-cytokeratin are identified as...
The Vascular Nature of PAS-Positive Patterns in Uveal Melanoma The Patterned Microcirculation of Uveal Melanoma: Is It Angiogenesis? In Vitro Observations: Aggressive Uveal Melanoma Cells Are Capable of Generating Patterned Vascular Channels in the Absence of Endothelial Cells through Vasculogenic Mimicry ...
The tumor cells stained positive for cytokeratin, ETS-related gene (ERG) and other vascular markers. Figure 7. View largeDownload slide A through F, An epithelioid angiosarcoma/ hemangioendothelioma from the left femur of a 76-year-old woman. Note that the tumor cells are positive for ...
cells, the capture molecules were first spotted in a single- and multi-array format onto aldehyde-coated glass slides. Tumor cell adhesion of EpCAMpos/neg cell lines was then determined and visualized by Coomassie/MitoTracker staining. In consequence, marginal binding of EpCAMlow/neg MDA-MB-231...
cells, the capture molecules were first spotted in a single- and multi-array format onto aldehyde-coated glass slides. Tumor cell adhesion of EpCAMpos/neg cell lines was then determined and visualized by Coomassie/MitoTracker staining. In consequence, marginal binding of EpCAMlow/neg MDA-MB-231...
) cell lines were positive for CD298. Human-specific EpCAM and pan-cytokeratin, which are commonly used to detect tumor cells26,27, were also tested but resulted in background staining of mouse bone marrow (data not shown). For flow cytometry analysis, gates were established based on ...
(C) Hematoxylin-eosin (H&E) slide, staining, and selection of ROIs for DSP. Green indicates pancytokeratin-positive tumor cells and light blue indicates SMA-positive stromal cells. (D) UMAP of DSP data of GC samples, stratified by site of tumor and ROIs (tumor vs stromal compartment). (...